CAS No.:6334-11-8
Name: 2,4,6-Trimethylaniline hydrochloride
Details Introduction
TOXICITY DATA with REFERENCE:
1. |
orl-rat LD50:660 mg/kg |
JPETAB Journal of Pharmacology and Experimental Therapeutics. 167 (1969),223. | ||
2. |
ipr-rat LD50:338 mg/kg |
NCIBR* Progress Report for Contract No. NIH-NCI-E-68-1311, Submitted to the National Cancer Institute by Bio-Research Consultants, Inc. (9 Commercial Ave., Cambridge, MA 02141) NIH-NCI-E-68-1311,10 ,1973. | ||
3. |
ipr-mus LD50:260 mg/kg |
NCIBR* Progress Report for Contract No. NIH-NCI-E-68-1311, Submitted to the National Cancer Institute by Bio-Research Consultants, Inc. (9 Commercial Ave., Cambridge, MA 02141) NIH-NCI-E-68-1311,10 ,1973. |
Consensus Reports:
IARC Cancer Review: Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 27 ,1982,p. 177.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) .
SAFETY PROFILE:
Suspected carcinogen with experimental carcinogenic and neoplastigenic data. Poison by intraperitoneal route. Moderately toxic by ingestion. When heated to decomposition 2,4,6-Trimethylaniline hydrochloride (CAS NO.6334-11-8) emits very toxic fumes of NOx and HCl.
Standards and Recommendations:
Analytical Methods:
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