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Current position:Home > Products > 2,4,6-Trimethylaniline hydrochloride

CAS No.:6334-11-8

Name: 2,4,6-Trimethylaniline hydrochloride

Details Introduction

TOXICITY DATA with REFERENCE:

1.    

orl-rat LD50:660 mg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 167 (1969),223.
2.    

ipr-rat LD50:338 mg/kg

    NCIBR*    Progress Report for Contract No. NIH-NCI-E-68-1311, Submitted to the National Cancer Institute by Bio-Research Consultants, Inc. (9 Commercial Ave., Cambridge, MA 02141) NIH-NCI-E-68-1311,10 ,1973.
3.    

ipr-mus LD50:260 mg/kg

    NCIBR*    Progress Report for Contract No. NIH-NCI-E-68-1311, Submitted to the National Cancer Institute by Bio-Research Consultants, Inc. (9 Commercial Ave., Cambridge, MA 02141) NIH-NCI-E-68-1311,10 ,1973.

Consensus Reports:

IARC Cancer Review: Animal Inadequate Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 27 ,1982,p. 177.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) .


SAFETY PROFILE:

Suspected carcinogen with experimental carcinogenic and neoplastigenic data. Poison by intraperitoneal route. Moderately toxic by ingestion. When heated to decomposition  2,4,6-Trimethylaniline hydrochloride (CAS NO.6334-11-8) emits very toxic fumes of NOx and HCl.


Standards and Recommendations:

 


Analytical Methods:

 


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