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CAS No.:97-02-9

Name: 2,4-DINITROANILINE

Details Introduction

TOXICITY DATA with REFERENCE：

1.	eye-rbt 500 mg/24H MLD	28ZPAK Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku Marhold, J.V.,Institut Pro Vychovu Vedoucicn Pracovniku Chemickeho Prumyclu Praha,Czechoslovakia.: 1972,132.
2.	mmo-sat 10 µg/plate	ENMUDM Environmental Mutagenesis. 5 (Suppl 1)(1983),3.
3.	mma-sat 2 µg/plate	MUREAV Mutation Research. 67 (1979),1.
4.	orl-rat LD50:285 mg/kg	TSCAT* Office of Toxic Substances Report. (U.S. Environmental Protection Agency, Office of Toxics Substances, 401M Street SW, Washington, DC 20460) OTS 206512 .
5.	ipr-rat LDLo:250 mg/kg	NCNSA6 National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. 5 (1953),32.
6.	orl-mus LD50:370 mg/kg	GTPZAB Gigiena Truda i Professionalnye Zabolevaniia. Labor Hygiene and Occupational Diseases. 25 (8)(1981),50.
7.	ipr-mus LDLo:400 mg/kg	JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. 48 (1959),419.
8.	orl-gpg LD50:1050 mg/kg	GISAAA Gigiena i Sanitariya. 47 (10)(1982),15.

guinea pig	LD50	oral	1050mg/kg (1050mg/kg)	Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 47(10), Pg. 15, 1982.
mouse	LD50	oral	370mg/kg (370mg/kg)	Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 25(8), Pg. 50, 1981.
mouse	LDLo	intraperitoneal	400mg/kg (400mg/kg)	Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 48, Pg. 419, 1959.
rat	LD50	oral	285mg/kg (285mg/kg)	Office of Toxic Substances Report. Vol. OTS,
rat	LDLo	intraperitoneal	250mg/kg (250mg/kg)	National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. Vol. 5, Pg. 32, 1953.

Consensus Reports：Reported in EPA TSCA Inventory.
SAFETY PROFILE：

Poison by ingestion and intraperitoneal routes. Experimental teratogenic and reproductive effects. Mutation data reported. An eye irritant. Combustible and explosive when exposed to heat or flame; can react with oxidizing materials. To fight fire, use CO₂, dry chemical. Mixtures with charcoal ignite at 350°C. Vigorous reaction with chlorine + hydrochloric acid evolves gases. When heated to decomposition it emits highly toxic fumes of NO_x.
Hazard Codes:
    T+: Very toxic
    N: Dangerous for the environment
Risk Statements about 2,4-DINITROANILINE(97-02-9):
    R33 Danger of cumulative effects.
    R26/27/28: Very toxic by inhalation, in contact with skin and if swallowed.
    R51/53: Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic
Safety Statements about 2,4-DINITROANILINE(97-02-9):
    S28 After contact with skin, wash immediately with plenty of soap-suds.
    S45 In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
    S61 Avoid release to the environment. Refer to special instructions / safety data sheets.
    S36/37: Wear suitable protective clothing and gloves.
    S28A After contact with skin, wash immediately with plenty of water.
Health Hazard: May cause headache, nausea, stupor. Irritating to skin and mucous membrane.

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CAS No.:97-02-9

Name: 2,4-DINITROANILINE