CAS No.:615-05-4

TOXICITY DATA with REFERENCE：

1.		skn-rbt 12,500 µg/24H MLD		FCTXAV    Food and Cosmetics Toxicology. 15 (1977),607.
2.		mma-sat 5 µg/plate		MUREAV    Mutation Research. 79 (1980),289.
3.		dnd-hmn:fbr 50 µmol/L		MUREAV    Mutation Research. 127 (1984),107.
4.		dnd-rat:lvr 500 µmol/L		CBINA8    Chemico-Biological Interactions. 31 (1980),35.
5.		sce-mus-ipr 12 mg/kg		MUREAV    Mutation Research. 108 (1983),225.
6.		orl-rat LD50:460 mg/kg		FCTXAV    Food and Cosmetics Toxicology. 15 (1977),607.
7.		ipr-rat LD50:116 mg/kg		BCPCA6    Biochemical Pharmacology. 30 (1981),2715.

Consensus Reports：

IARC Cancer Review: Group 2B IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 (1987),p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Human Limited Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 27 (1982),p. 103.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . EPA Genetic Toxicology Program. Reported in EPA TSCA Inventory.

SAFETY PROFILE：

Confirmed carcinogen. Poison by intraperitoneal route. Moderately toxic by ingestion. Experimental reproductive effects. Human mutation data reported. A skin irritant. When heated to decomposition it emits toxic fumes of NO_x. See also 2,4-DIAMINOANISOLE DIHYDROCHLORIDE; 2,4-DIAMINOANISOLE SULFATE.
Hazard Codes : T: Toxic
N: Dangerous for the environment
Risk Statements : 45: May cause cancer
22: Harmful if swallowed
51/53: Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment
68: Possible risk of irreversible effects 
Safety Statements : 53: Avoid exposure - obtain special instruction before use
45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
61: Avoid release to the environment. Refer to special instructions safety data sheet 
RIDADR : 2811
HazardClass : 6.1(b)
PackingGroup : III

Standards and Recommendations：

DFG MAK: Animal Carcinogen, Suspected Human Carcinogen
NIOSH REL: (2,4-diaminoanisole) Reduce to lowest feasible level

Analytical Methods：