CAS No.:95-68-1
Name: 2,4-Dimethyl aniline
Details Introduction
TOXICITY DATA with REFERENCE:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LC50 | inhalation | 149ppm/7H (149ppm) | "Documentation of the Threshold Limit Values and Biological Exposure Indices," 5th ed., Cincinnati, OH, American Conference of Governmental Industrial Hygienists, Inc., 1986Vol. 6, Pg. 1743, 1991. | |
mouse | LD50 | oral | 250mg/kg (250mg/kg) | National Technical Information Service. Vol. PB214-270, | |
rat | LD50 | oral | 467mg/kg (467mg/kg) | National Technical Information Service. Vol. PB214-270, |
Consensus Reports:
IARC Cancer Review: Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 ,1987,p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 16 ,1978,p. 367.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . Reported in EPA TSCA Inventory.
SAFETY PROFILE:
Suspected carcinogen. Poison by ingestion. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
Hazard Codes: T, N
Risk Statements: 23/24/25-33-51/53
R23/24/25: Toxic by inhalation, in contact with skin and if swallowed.
R33: Danger of cumulative effects.
R51/53: Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Safety Statements: 28-36/37-45-61
S28: After contact with skin, wash immediately with plenty of soap-suds.
S36/37: Wear suitable protective clothing and gloves.
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S61: Avoid release to the environment. Refer to special instructions / safety data sheets.
RIDADR: UN 1711 6.1/PG 2
WGK Germany: 2
RTECS: ZE8925000
HazardClass: 6.1
PackingGroup 2,4-Xylidine (CAS NO.95-68-1): II
Standards and Recommendations:
DFG MAK: Animal Carcinogen, Suspected Human Carcinogen
Analytical Methods:
For occupational chemical analysis use NIOSH: Amines, Aromatic, 2002.
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