CAS No.:121-88-0

TOXICITY DATA with REFERENCE：

1.		mmo-sat 20 μg/plate		PNASA6    Proceedings of the National Academy of Sciences of the United States of America. 72 (1975),2423.
2.		mma-sat 1 μmol/plate		MUREAV    Mutation Research. 58 (1978),11.
3.		cyt-ham:lng 1 mg/L		ATSUDG    Archives of Toxicology,Supplement (4)(1980),41.
4.		orl-rat TDLo:3756 mg/kg/16D-I:ETA,REP
5.		orl-rat LD50:>4 g/kg		JTEHD6    Journal of Toxicology and Environmental Health. 2 (1977),657.
6.		ipr-rat LD50:>800 mg/kg		JTEHD6    Journal of Toxicology and Environmental Health. 2 (1977),657. NTPTR*    National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No. NTP-TR-334 ,1988.
7.		orl-rat TDLo:52 g/kg/13W-I		NTPTR*    National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No. NTP-TR-334 ,1988.
8.		orl-mus TDLo:104 g/kg/13W-I		NTPTR*    National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No. NTP-TR-334 ,1988.

Consensus Reports：

IARC Cancer Review: Group 3 IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of chemicals to Man . 57 (1993),p. 177.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Limited Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of chemicals to Man . 57 (1993),p. 177.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Human Inadequate Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of chemicals to Man . 57 (1993),p. 177.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . NTP Carcinogenesis Studies (gavage): Some Evidence: rat NTPTR*    National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No. NTP-TR-334 ,1988. . Reported in EPA TSCA Inventory. EPA Genetic Toxicology Program.

SAFETY PROFILE：

Questionable carcinogen with experimental tumorigenic data. Experimental reproductive effects. Mutation data reported. Potentially explosive reaction with nitrous acid. When heated to decomposition it emits toxic fumes of NO_x.
Hazard Codes: XnXi
Risk Statements: 36/37/38-68-20/21/22 
R36/37/38: Irritating to eyes, respiratory system and skin
R68: Possible risk of irreversible effects
R20/21/22: Harmful by inhalation, in contact with skin and if swallowed
Safety Statements: 26-36/37-45-36/37/39-36 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36/37: Wear suitable protective clothing and gloves
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) 
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection
S36: Wear suitable protective clothing
RIDADR: 2811
WGK Germany: 2
RTECS: SJ6302500

Standards and Recommendations：

 

Analytical Methods：