CAS No.:15892-23-6
Name: 2-Butanol
Details Introduction
TOXICITY DATA with REFERENCE:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
dog | LDLo | oral | 2400mg/kg (2400mg/kg) | National Technical Information Service. Vol. OTS0572377, | |
frog | LDLo | parenteral | 15gm/kg (15000mg/kg) |
Peripheral nerve and sensation: spastic paralysis with or without sensory change behavioral: somnolence (general depressed activity) |
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 50, Pg. 296, 1935. |
guinea pig | LD50 | intraperitoneal | 1067mg/kg (1067mg/kg) | EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985. | |
hamster | LD50 | intraperitoneal | 1218mg/kg (1218mg/kg) | EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985. | |
mouse | LD50 | intraperitoneal | 771mg/kg (771mg/kg) | Shell Chemical Company. Unpublished Report. Vol. -, Pg. 2, 1961. | |
mouse | LD50 | intravenous | 764mg/kg (764mg/kg) | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 135, Pg. 330, 1962. | |
rabbit | LD50 | intraperitoneal | 277mg/kg (277mg/kg) | EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985. | |
rabbit | LD50 | oral | 4893mg/kg (4893mg/kg) |
Sense organs and special senses: corneal damage: eye lungs, thorax, or respiration: dyspnea cardiac: pulse rate |
Industrial Medicine and Surgery. Vol. 41, Pg. 31, 1972. |
rat | LCLo | inhalation | 16000ppm/4H (16000ppm) | Sense organs and special senses: other changes: olfaction behavioral: somnolence (general depressed activity) lungs, thorax, or respiration: other changes | Shell Chemical Company. Vol. MSDS-5280-4, |
rat | LD50 | intraperitoneal | 1193mg/kg (1193mg/kg) | EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985. | |
rat | LD50 | intravenous | 138mg/kg (138mg/kg) | EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985. | |
rat | LD50 | oral | 2193mg/kg (2193mg/kg) |
Behavioral: somnolence (general depressed activity) behavioral: ataxia behavioral: coma |
National Technical Information Service. Vol. OTS0557575, |
rat | LD50 | skin | > 2gm/kg (2000mg/kg) | National Technical Information Service. Vol. OTS0557575, |
Consensus Reports:
SAFETY PROFILE:
Hazard Codes:
Xi: Irritant
Risk Statements:
R10:Flammable.
R36/37:Irritating to eyes and respiratory system.
R67:Vapours may cause drowsiness and dizziness.
Safety Statements:
S13:Keep away from food, drink and animal foodstuffs.
S24/25:Avoid contact with skin and eyes.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S46:If swallowed, seek medical advice immediately and show this container or label.
S7/9:Keep container tightly closed and in a well-ventilated place.
RIDADR: UN 1120 3/PG 3
WGK Germany: 1
RTECS: EO1750000
Standards and Recommendations:
Analytical Methods:
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