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Current position:Home > Products > 2-Butanol

CAS No.:15892-23-6

Name: 2-Butanol

Details Introduction

TOXICITY DATA with REFERENCE:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LDLo oral 2400mg/kg (2400mg/kg)   National Technical Information Service. Vol. OTS0572377,
frog LDLo parenteral 15gm/kg (15000mg/kg)

Peripheral nerve and sensation: spastic paralysis with or without sensory change behavioral: somnolence (general depressed activity)

Archives Internationales de Pharmacodynamie et de Therapie. Vol. 50, Pg. 296, 1935.
guinea pig LD50 intraperitoneal 1067mg/kg (1067mg/kg)   EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985.
hamster LD50 intraperitoneal 1218mg/kg (1218mg/kg)   EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985.
mouse LD50 intraperitoneal 771mg/kg (771mg/kg)   Shell Chemical Company. Unpublished Report. Vol. -, Pg. 2, 1961.
mouse LD50 intravenous 764mg/kg (764mg/kg)   Archives Internationales de Pharmacodynamie et de Therapie. Vol. 135, Pg. 330, 1962.
rabbit LD50 intraperitoneal 277mg/kg (277mg/kg)   EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985.
rabbit LD50 oral 4893mg/kg (4893mg/kg)

Sense organs and special senses: corneal damage: eye lungs, thorax, or respiration: dyspnea cardiac: pulse rate

Industrial Medicine and Surgery. Vol. 41, Pg. 31, 1972.
rat LCLo inhalation 16000ppm/4H (16000ppm) Sense organs and special senses: other changes: olfaction behavioral: somnolence (general depressed activity) lungs, thorax, or respiration: other changes Shell Chemical Company. Vol. MSDS-5280-4,
rat LD50 intraperitoneal 1193mg/kg (1193mg/kg)   EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985.
rat LD50 intravenous 138mg/kg (138mg/kg)   EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985.
rat LD50 oral 2193mg/kg (2193mg/kg)

Behavioral: somnolence (general depressed activity) behavioral: ataxia behavioral: coma

National Technical Information Service. Vol. OTS0557575,
rat LD50 skin > 2gm/kg (2000mg/kg)   National Technical Information Service. Vol. OTS0557575,


Consensus Reports:

 


SAFETY PROFILE:

Hazard Codes:
Xi: Irritant
Risk Statements:
R10:Flammable.  
R36/37:Irritating to eyes and respiratory system. 
R67:Vapours may cause drowsiness and dizziness. 
Safety Statements:
S13:Keep away from food, drink and animal foodstuffs.  
S24/25:Avoid contact with skin and eyes. 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S46:If swallowed, seek medical advice immediately and show this container or label. 
S7/9:Keep container  tightly closed and in a well-ventilated place.
RIDADR: UN 1120 3/PG 3
WGK Germany: 1
RTECS: EO1750000


Standards and Recommendations:

 


Analytical Methods:

 


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