CAS No.:109-09-1
Name: 2-Chloropyridine
Details Introduction
TOXICITY DATA with REFERENCE:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
bird - wild | LD50 | oral | 1gm/kg (1000mg/kg) | Archives of Environmental Contamination and Toxicology. Vol. 12, Pg. 355, 1983. | |
mouse | LD50 | intraperitoneal | 130mg/kg (130mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: ANTIPSYCHOTIC LIVER: FATTY LIVER DEGERATION |
Toxicology and Applied Pharmacology. Vol. 11, Pg. 361, 1967. |
mouse | LD50 | oral | 110mg/kg (110mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: ANTIPSYCHOTIC LIVER: OTHER CHANGES |
Toxicology and Applied Pharmacology. Vol. 11, Pg. 361, 1967. |
rabbit | LD50 | intraperitoneal | 48mg/kg (48mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LIVER: FATTY LIVER DEGERATION BEHAVIORAL: ANTIPSYCHOTIC |
Toxicology and Applied Pharmacology. Vol. 11, Pg. 361, 1967. |
rabbit | LD50 | skin | 64mg/kg (64mg/kg) | LIVER: OTHER CHANGES | Toxicology and Applied Pharmacology. Vol. 11, Pg. 361, 1967. |
rat | LCLo | inhalation | 100ppm/4H (100ppm) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: ANTIPSYCHOTIC LIVER: OTHER CHANGES |
Toxicology and Applied Pharmacology. Vol. 11, Pg. 361, 1967. |
Consensus Reports:
Reported in EPA TSCA Inventory.
SAFETY PROFILE:
Safty information about 2-Chloropyridine (CAS NO.109-09-1) is:
Poison by ingestion, inhalation, skin contact, and intraperitoneal routes. Combustible when exposed to heat or flame. Can react with oxidizing materials. When heated to decomposition it emits very toxic fumes of Cl−, NOx, and phosgene.
Hazard Codes: T
Risk Statements: 23/24/25-36/37/38
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36/37/39-45-28A-27
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S28:After contact with skin, wash immediately with plenty of soap-suds.
S27:Take off immediately all contaminated clothing.
RIDADR: UN 2822 6.1/PG 2
WGK Germany: 3
RTECS: US5950000
Hazard Note: Toxic
HazardClass: 6.1
PackingGroup: II
HS Code: 29333999
Standards and Recommendations:
Analytical Methods:
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