CAS No.:131-89-5
Name: 2-Cyclohexyl-4,6-Dinitrophenol
Details Introduction
TOXICITY DATA with REFERENCE:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
chicken | LD50 | oral | 76mg/kg (76mg/kg) | National Technical Information Service. Vol. OTS0536145, | |
dog | LDLo | intravenous | 8mg/kg (8mg/kg) | cardiac: arrhythmias (including changes in conduction) lungs, thorax, or respiration: dyspnea | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 50, Pg. 20, 1935. |
dog | LDLo | subcutaneous | 20mg/kg (20mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 53, Pg. 58, 1935. | |
guinea pig | LD50 | oral | 50mg/kg (50mg/kg) | Pesticide Chemicals Official Compendium, Association of the American Pesticide Control Officials, Inc., 1966. Vol. -, Pg. 417, 1966. | |
guinea pig | LDLo | skin | 1gm/kg (1000mg/kg) | Pesticide Chemicals Official Compendium, Association of the American Pesticide Control Officials, Inc., 1966. Vol. -, Pg. 417, 1966. | |
guinea pig | LDLo | subcutaneous | 20mg/kg (20mg/kg) | Pesticide Chemicals Official Compendium, Association of the American Pesticide Control Officials, Inc., 1966. Vol. -, Pg. 417, 1966. | |
mammal (species unspecified) | LD50 | unreported | 50mg/kg (50mg/kg) | "Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag New York, Inc., 1971Vol. -, Pg. 101, 1971. | |
mouse | LD50 | intraperitoneal | 25mg/kg (25mg/kg) | Biochemical Pharmacology. Vol. 18, Pg. 1389, 1969. | |
mouse | LD50 | oral | 50mg/kg (50mg/kg) | "Wirksubstanzen der Pflanzenschutz und Schadlingsbekampfungsmittel," Perkow, W., Berlin, Verlag Paul Parey, 1971-1976Vol. -, Pg. -, 1971/1976. | |
mouse | LDLo | subcutaneous | 30mg/kg (30mg/kg) | lungs, thorax, or respiration: other changes | University of California, Berkeley, Publications in Pharmacology. Vol. 1, Pg. 151, 1939. |
pigeon | LD50 | intramuscular | 8mg/kg (8mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 53, Pg. 58, 1935. | |
pigeon | LDLo | intravenous | 7mg/kg (7mg/kg) | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 50, Pg. 20, 1935. | |
rabbit | LD50 | oral | 81mg/kg (81mg/kg) | National Technical Information Service. Vol. OTS0536145, | |
rabbit | LDLo | subcutaneous | 40mg/kg (40mg/kg) | behavioral: convulsions or effect on seizure threshold lungs, thorax, or respiration: other changes | University of California, Berkeley, Publications in Pharmacology. Vol. 1, Pg. 151, 1939. |
rat | LD50 | oral | 65mg/kg (65mg/kg) | Agricultural Research Service, USDA Information Memorandum. Vol. 20, Pg. 9, 1966. |
Consensus Reports:
SAFETY PROFILE:
A poison by ingestion, intraperitoneal, intravenous, subcutaneous, and possibly other routes. Moderately toxic by skin contact. A skin irritant. Fire hazard. See also NITRATES and PHENOLS. Can react with oxidizers. When heated to decomposition it emits toxic fumes of NOx.
Hazard Codes:
T
N
Risk Statements:
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed.
R50/53:Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Safety Statements:
S13:Keep away from food, drink and animal foodstuffs.
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S60:This material and its container must be disposed of as hazardous waste.
S61:Avoid release to the environment. Refer to special instructions / safety data sheets.
RIDADR: 2779
HazardClass: 6.1(b)
PackingGroup: III
Standards and Recommendations:
Analytical Methods:
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