CAS No.:110-80-5
Name: 2-Ethoxyethanol
Details Introduction
TOXICITY DATA with REFERENCE:
1. |
eye-hmn 6000 ppm |
PHRPA6 Public Health Reports. 45 (1930),1459. | ||
2. |
skn-rbt 500 mg open MLD |
UCDS** Union Carbide Data Sheet. (Industrial Medicine and Toxicology Dept., Union Carbide Corp., 270 Park Ave., New York, NY 10017) 5/20 ,1966. | ||
3. |
eye-rbt 500 mg/24H MLD |
85JCAE Prehled Prumyslove Toxikologie; Organicke Latky Marhold, J.,Prague, Czechoslovakia.: Avicenum,1986,624. | ||
4. |
eye-rbt 50 mg MOD |
UCDS** Union Carbide Data Sheet. (Industrial Medicine and Toxicology Dept., Union Carbide Corp., 270 Park Ave., New York, NY 10017) 5/20 ,1966. | ||
5. |
eye-gpg 10 μg MLD |
JPPMAB Journal of Pharmacy and Pharmacology. 11 (1959),150. | ||
6. |
orl-rat LD50:2125 mg/kg |
GTPZAB Gigiena Truda i Professionalnye Zabolevaniia. Labor Hygiene and Occupational Diseases. 32 (3)(1988),48. | ||
7. |
ihl-rat LC50:2000 ppm/7H |
NPIRI* Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. 1 (1974),54. | ||
8. |
skn-rat LD50:3900 mg/kg |
TOXID9 Toxicologist. 4 (1984),180. | ||
9. |
ipr-rat LD50:2800 mg/kg |
ARZNAD Arzneimittel-Forschung. Drug Research. 21 (1971),880. | ||
10. |
|
Consensus Reports:
Reported in EPA TSCA Inventory. Glycol ether compounds are on the Community Right-To-Know List.
SAFETY PROFILE:
Hazard Codes: T
Risk Statements: 60-61-10-20/21/22
R60:May impair fertility.
R61:May cause harm to the unborn child.
R10:Flammable.
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
Safety Statements: 53-45
S53:Avoid exposure - obtain special instructions before use.
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR: UN 1171 3/PG 3
WGK Germany: 1
RTECS: KK8050000
HazardClass: 3
PackingGroup: III
Moderately toxic by ingestion, skin contact, intravenous, and intraperitoneal routes. Mildly toxic by inhalation and subcutaneous routes. An experimental teratogen. Other experimental reproductive effects. A mild eye and skin irritant. Combustible when exposed to heat or flame; can react with oxidizing materials. Moderate explosion hazard in the form of vapor when exposed to heat or flame. Mixture with hydrogen peroxide + polyacrylamide gel + toluene is explosive when dry. To fight fire, use alcohol foam, dry chemical. See also GLYCOL ETHERS.
Standards and Recommendations:
OSHA PEL: TWA 200 ppm (skin)
ACGIH TLV: TWA 5 ppm (skin); BEI: 100 mg/g creatinine of 2-ethoxyacetic acid in urine end of shift at end of workweek
DFG MAK: 5 ppm (19 mg/m3)
NIOSH REL: (Glycol Ethers) Reduce to lowest level
DOT Classification: 3; Label: Flammable Liquid
Analytical Methods:
For occupational chemical analysis use OSHA: #53 or NIOSH: Alcohols IV, 1403.
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