CAS No.:109-85-3

TOXICITY DATA with REFERENCE：

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	400mg/kg (400mg/kg)		National Technical Information Service. Vol. AD691-490,
mouse	LDLo	oral	1600mg/kg (1600mg/kg)	behavioral: tremor behavioral: muscle weakness behavioral: ataxia	National Technical Information Service. Vol. OTS0546426,
rat	LDLo	oral	1600mg/kg (1600mg/kg)	behavioral: muscle weakness lungs, thorax, or respiration: dyspnea lungs, thorax, or respiration: cyanosis	National Technical Information Service. Vol. OTS0546426,

Consensus Reports：

Reported in EPA TSCA Inventory.

SAFETY PROFILE：

Poison by intraperitoneal route. When heated to decomposition it emits toxic fumes of NO_x. See also AMINES. 
Hazard Codes:
F
C
Risk Statements:
R11:Highly flammable. 
R34:Causes burns.
Safety Statements:
S16:Keep away from sources of ignition. 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection. 
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR: UN 2733 3/PG 2
WGK Germany: 3
RTECS: KR8750000
HazardClass: 3
PackingGroup: II

Standards and Recommendations：

 

Analytical Methods：

By glycol monomethyl ether and ammonia in the nickel or alumina catalysts under high-temperature dehydration in, or methicillin-acetonitrile nickel to be catalytic hydrogenation.