CAS No.:1769-24-0
Name: 2-Methyl-4(3H)-quinazolinone
Details Introduction
TOXICITY DATA with REFERENCE:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | 592mg/kg (592mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 12, Pg. 1204, 1962. | |
mouse | LD50 | oral | 859mg/kg (859mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 12, Pg. 1204, 1962. | |
mouse | LD50 | parenteral | 500mg/kg (500mg/kg) | autonomic nervous system: "smooth muscle relaxant (mechanism undefined, spasmolytic)" behavioral: tremor behavioral: muscle weakness | Pharmaceutical Chemistry Journal Vol. 7, Pg. 626, 1973. |
Consensus Reports:
SAFETY PROFILE:
Moderately toxic by ingestion, intraperitoneal and parenteral routes. When heated to decomposition it emits toxic fumes of NOx.
Hazard Codes:
Xi
Risk Statements:
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements:
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S37/39:Wear suitable gloves and eye/face protection.
WGK Germany: 3
RTECS: VA3677000
Standards and Recommendations:
Analytical Methods:
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