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Current position:Home > Products > 2-Methyl-4(3H)-quinazolinone

CAS No.:1769-24-0

Name: 2-Methyl-4(3H)-quinazolinone

Details Introduction

TOXICITY DATA with REFERENCE:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 592mg/kg (592mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 12, Pg. 1204, 1962.
mouse LD50 oral 859mg/kg (859mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 12, Pg. 1204, 1962.
mouse LD50 parenteral 500mg/kg (500mg/kg) autonomic nervous system: "smooth muscle relaxant (mechanism undefined, spasmolytic)" behavioral: tremor behavioral: muscle weakness Pharmaceutical Chemistry Journal Vol. 7, Pg. 626, 1973.

Consensus Reports:

 


SAFETY PROFILE:

Moderately toxic by ingestion, intraperitoneal and parenteral routes. When heated to decomposition it emits toxic fumes of NOx
Hazard Codes:
IrritantXi
Risk Statements:
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements:
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S37/39:Wear suitable gloves and eye/face protection.
WGK Germany: 3
RTECS: VA3677000


Standards and Recommendations:

 


Analytical Methods:

 


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