CAS No.:94-74-6
Name: 2-Methyl-4-chlorophenoxyacetic acid
Details Introduction
TOXICITY DATA with REFERENCE:
1. |
sln-dmg-orl 5 mmol/L |
EXPEAM Experientia. 30 (1974),621. | ||
2. |
mmo-smc 30 µmol/L/3H |
MUREAV Mutation Research. 60 (1979),291. | ||
3. |
dns-mus-orl 200 mg/kg |
MUREAV Mutation Research. 55 (1978),197. | ||
4. |
hma-mus/sat 200 mg/kg |
ECBUDQ Ecological Bulletins. 27 (1978),182. | ||
5. |
sce-ham:ovr 10 µmol/L/1H |
CRNGDP Carcinogenesis. 5 (1984),703. | ||
6. |
orl-mus TDLo:1 g/kg (6-15D preg):TER |
ARZNAD Arzneimittel-Forschung. Drug Research. 33 (1983),1479. | ||
7. |
orl-man LDLo:814 mg/kg:CNS,CVS |
BMJOAE British Medical Journal. 2 (1965),629. | ||
8. |
orl-rat LD50:700 mg/kg |
AJVRAH American Journal of Veterinary Research. 15 (1954),622. | ||
9. |
orl-mus LD50:439 mg/kg |
RPZHAW Roczniki Panstwowego Zakladu Higieny. 31 (1980),373. | ||
10. |
scu-mus LDLo:28 mg/kg |
PCOC** Pesticide Chemicals Official Compendium ,Association of the American Pesticide Control Officials, Inc.Topeka, KS.: 1966,711. | ||
Consensus Reports:IARC Cancer Review: Group 2B IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 , 1987,p. 156.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 30 , 1983,p. 255.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Human Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 30 , 1983,p. 255.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Human Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 41 , 1986,p. 357.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . Reported in EPA TSCA Inventory. EPA Genetic Toxicology Program.
SAFETY PROFILE:
Suspected carcinogen. Poison by subcutaneous and intravenous routes. Moderately toxic by ingestion. Human systemic effects by ingestion: blood pressure decrease and coma. Experimental teratogenic and reproductive effects. Mutation data reported. An herbicide. When heated to decomposition it emits toxic fumes of Cl−.
Hazard Codes: Xn,F
Risk Statements: 22-38-41-36-20/21/22-11
22: Harmful if swallowed
38: Irritating to the skin
41: Risk of serious damage to eyes
36: Irritating to the eyes
20/21/22: Harmful by inhalation, in contact with skin and if swallowed
11: Highly Flammable
Safety Statements: 26-37-39-36-16
26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
37: Wear suitable gloves
39: Wear eye/face protection
36: Wear suitable protective clothing
16: Keep away from sources of ignition - No smoking
RIDADR UN: 2765
WGK Germany: 2
RTECS AG: 1575000
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