CAS No.:4812-23-1
Name: 2-Nitro-2-butene
Details Introduction
TOXICITY DATA with REFERENCE：
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| rabbit | LDLo | skin | 620mg/kg (620mg/kg) | BEHAVIORAL: TREMOR BEHAVIORAL: TETANY LUNGS, THORAX, OR RESPIRATION: DYSPNEA |
Industrial Medicine and Surgery. Vol. 34, Pg. 800, 1965. |
| rat | LCLo | inhalation | 1400ppm (1400ppm) | SENSE ORGANS AND SPECIAL SENSES: IRITIS: EYE LUNGS, THORAX, OR RESPIRATION: CYANOSIS VASCULAR: REGIONAL OR GENERAL ARTERIOLAR OR VENOUS DILATION |
AMA Archives of Industrial Health. Vol. 18, Pg. 312, 1958. |
| rat | LDLo | intraperitoneal | 80mg/kg (80mg/kg) | Toxicology and Applied Pharmacology. Vol. 1, Pg. 156, 1959. |
Consensus Reports：
SAFETY PROFILE：
Poison by ingestion and intraperitoneal routes. Moderately toxic by skin contact and inhalation. A human eye irritant and severe experimental eye and skin irritant. An unstable compound. When 2-Nitro-2-butene (CAS NO.4812-23-1) is heated to decomposition it emits toxic fumes of NOx. See also NITRO COMPOUNDS.
Standards and Recommendations：
Analytical Methods：
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