CAS No.:581-89-5
Name: 2-Nitronaphthalene
Details Introduction
TOXICITY DATA with REFERENCE:
1. |
mmo-sat 1 µg/plate |
MUREAV Mutation Research. 122 (1983),243. | ||
2. |
mrc-smc 1 pph |
JJIND8 JNCI, Journal of the National Cancer Institute. 62 (1979),901. | ||
3. |
orl-dog TDLo:2400 mg/kg/34/W-I:ETA |
XPHCI* U.S. Public Health Service, Current Intelligence Bulletin. (National Institute for Occupational Safety and Health, 5600 Fishers Lane, Rockville, MD 20857) 17DEC76 . | ||
4. |
orl-rat LD50:4400 mg/kg |
34ZIAG Toxicology of Drugs and Chemicals ,Deichmann, W.B.,New York, NY.: Academic Press, Inc.,1969,428. | ||
5. |
ipr-mus LD50:1300 mg/kg |
JJIND8 JNCI, Journal of the National Cancer Institute. 62 (1979),911. | ||
6. |
orl-rbt LD50:2650 mg/kg |
34ZIAG Toxicology of Drugs and Chemicals ,Deichmann, W.B.,New York, NY.: Academic Press, Inc.,1969,428. |
Consensus Reports:
IARC Cancer Review: Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 46 ,1989,p. 303.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 46 ,1989,p. 303.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 46 ,1989,p. 303.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . EPA Genetic Toxicology Program.
SAFETY PROFILE:
Confirmed carcinogen with experimental tumorigenic data. Moderately toxic by ingestion and intraperitoneal routes. Mutation data reported. A skin and lung irritant. For explosion and disaster hazards, see NITRATES. Combustible when exposed to heat or flame. When heated to decomposition it emits toxic fumes of NOx. See also 1-NITRONAPHTHALENE.
Hazard Codes of 2-Nitronaphthalene (CAS NO.581-89-5): T,N
Risk Statements: 45-51/53
R41:Risk of serious damage to the eyes.
R51/53:Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Safety Statements: 53-45-61-60
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S53:Avoid exposure - obtain special instructions before use.
S60:This material and its container must be disposed of as hazardous waste.
S61:Avoid release to the environment. Refer to special instructions / safety data sheets.
Standards and Recommendations:
DFG MAK: DFG TRK: Animal Carcinogen, Suspected Human Carcinogen
NIOSH REL: (2-Nitronaphthalene) lowest feasible conc
Analytical Methods:
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