CAS No.:90-43-7

TOXICITY DATA with REFERENCE：

1.		skn-rbt 250 mg		MccSB#    Personal Communication from Susan B. McCollister, Dow Chemical U.S.A., Midland, MI 48640, to NIOSH, Cincinnati, OH 45226, June 15, 1984 15JUN84
2.		skn-rbt 20 mg/24H MOD		85JCAE    Prehled Prumyslove Toxikologie; Organicke Latky Marhold, J.,Prague, Czechoslovakia.: Avicenum,1986,228.
3.		eye-rbt 50 µg/24H SEV		85JCAE    Prehled Prumyslove Toxikologie; Organicke Latky Marhold, J.,Prague, Czechoslovakia.: Avicenum,1986,228.
4.		mmo-sat 60 µg/plate		ENMUDM    Environmental Mutagenesis. 5 (Suppl 1)(1983),3.
5.		cyt-hmn:fbr 200 µg/L		MUREAV    Mutation Research. 54 (1978),255.
6.		msc-hmn:emb 20 mg/L		MUREAV    Mutation Research. 156 (1985),123.
7.		msc-hmn:oth 15 mg/L		TRENAF    Kenkyu Nenpo-Tokyo-toritsu Eisei Kenkyusho. 35 (1984),399.
8.		cyt-ham:ovr 100 mg/L		MUREAV    Mutation Research. 141 (1984),95.
9.		orl-rat LD50:2000 mg/kg		NNGADV    Nippon Noyaku Gakkaishi. 3 (1978),365.
10.		unr-rat LD50:2700 mg/kg		TRENAF    Kenkyu Ne

Consensus Reports：

IARC Cancer Review: Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man 7 (1987),p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon. France.: ) (single copies can be ordered from WHO Publications centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Inadequate Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man 30 (1983),p. 329.(World Health Organization, Internation Agency for Research on Cancer,Lyon. France.: ) (single copies can be ordered from WHO Publications centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; NTP Carcinogenesis Studies (dermal); No Evidence: mouse NTPTR*    National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No. NTP-TR-301,86 . . Reported in EPA TSCA Inventory. On Community Right-To-Know List.

SAFETY PROFILE：

Hazard Codes: Xi, N
Risk Statements: 36/37/38-50-37/38/50-36 
R36/37/38:Irritating to eyes, respiratory system and skin. 
R50:Very toxic to aquatic organisms. 
R37/38:Irritating to respiratory system and skin. 
R36:Irritating to eyes.
Safety Statements: 22-61 
S22:Do not breathe dust. 
S61:Avoid release to the environment. Refer to special instructions / safety data sheets.
RIDADR: UN 3077 9/PG 3
WGK Germany: 2
RTECS: DV5775000
HazardClass: 9
PackingGroup: III
HS Code: 29071900
A poison by intraperitoneal route. Moderately toxic by ingestion and possibly other routes. An experimental teratogen. Other experimental reproductive effects. Human mutation data reported. Severe eye and moderate skin irritant. Questionable carcinogen with experimental carcinogenic data. When heated to decomposition it emits acrid smoke and irritating fumes.

Standards and Recommendations：

 

Analytical Methods：