CAS No.:106-43-4
Name: 4-chlorotoluene
Details Introduction
TOXICITY DATA with REFERENCE:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
guinea pig | LD50 | unreported | 3750mg/kg (3750mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: EXCITEMENT LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION |
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 46(2), Pg. 67, 1981. |
mouse | LC50 | inhalation | 34gm/m3/2H (34000mg/m3) | "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 38, 1982. | |
mouse | LD50 | oral | 1900mg/kg (1900mg/kg) | "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 38, 1982. | |
mouse | LD50 | unreported | 4gm/kg (4000mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION BEHAVIORAL: EXCITEMENT |
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 46(2), Pg. 67, 1981. |
rat | LD50 | oral | 2100mg/kg (2100mg/kg) | BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) LUNGS, THORAX, OR RESPIRATION: CYANOSIS GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS |
Office of Toxic Substances Report. Vol. OTS0513162, |
rat | LD50 | unreported | 4gm/kg (4000mg/kg) | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 45(12), Pg. 64, 1980. |
Consensus Reports:
SAFETY PROFILE:
Safety Information of 4-chlorotoluene (CAS NO.106-43-4):
Hazard Codes: Xn,N,T,F
Risk Statements: 20-51/53-39/23/24/25-23/24/25-11-10
R20:Harmful by inhalation.
R51/53:Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
R39:Danger of very serious irreversible effects.
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed.
R11:Highly flammable.
R10:Flammable.
Safety Statements: 24/25-61-45-36/37-16-7
S24/25:Avoid contact with skin and eyes.
S61:Avoid release to the environment. Refer to special instructions / safety data sheets.
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S36/37:Wear suitable protective clothing and gloves.
S16:Keep away from sources of ignition.
S7:Keep container tightly closed.
RIDADR: UN 2238 3/PG 3
WGK Germany: 2
RTECS: XS9010000
Hazard Note: Harmful
HazardClass: 3
PackingGroup: III
HS Code: 29036990
Standards and Recommendations:
Analytical Methods:
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