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Current position:Home > Products > 4-chlorotoluene

CAS No.:106-43-4

Name: 4-chlorotoluene

Details Introduction

TOXICITY DATA with REFERENCE:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LD50 unreported 3750mg/kg (3750mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: EXCITEMENT

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 46(2), Pg. 67, 1981.
mouse LC50 inhalation 34gm/m3/2H (34000mg/m3)   "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 38, 1982.
mouse LD50 oral 1900mg/kg (1900mg/kg)   "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 38, 1982.
mouse LD50 unreported 4gm/kg (4000mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

BEHAVIORAL: EXCITEMENT
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 46(2), Pg. 67, 1981.
rat LD50 oral 2100mg/kg (2100mg/kg) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

LUNGS, THORAX, OR RESPIRATION: CYANOSIS

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS
Office of Toxic Substances Report. Vol. OTS0513162,
rat LD50 unreported 4gm/kg (4000mg/kg)   Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 45(12), Pg. 64, 1980.


Consensus Reports:

 


SAFETY PROFILE:

Safety Information of 4-chlorotoluene (CAS NO.106-43-4):
Hazard Codes: XnHarmful,NDangerous,TToxic,FFlammable
Risk Statements: 20-51/53-39/23/24/25-23/24/25-11-10  
R20:Harmful by inhalation. 
R51/53:Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. 
R39:Danger of very serious irreversible effects. 
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed. 
R11:Highly flammable. 
R10:Flammable.
Safety Statements: 24/25-61-45-36/37-16-7 
S24/25:Avoid contact with skin and eyes. 
S61:Avoid release to the environment. Refer to special instructions / safety data sheets. 
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) 
S36/37:Wear suitable protective clothing and gloves. 
S16:Keep away from sources of ignition. 
S7:Keep container tightly closed.
RIDADR: UN 2238 3/PG 3
WGK Germany: 2
RTECS: XS9010000
Hazard Note: Harmful
HazardClass: 3
PackingGroup: III
HS Code: 29036990


Standards and Recommendations:

 


Analytical Methods:

 


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