CAS No.:1131-18-6
Name: 5-Amino-3-methyl-1-phenylpyrazole
Details Introduction
TOXICITY DATA with REFERENCE:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | oral | 1300mg/kg (1300mg/kg) | BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS" BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) |
Personal Communication from LONZA Ltd., CH-4002, Basel, SwitzerlandVol. 03FEB1981, |
mouse | LDLo | intraperitoneal | 800mg/kg (800mg/kg) | Farmakologiya i Toksikologiya Vol. 27, Pg. 295, 1964. | |
rabbit | LD50 | oral | 1gm/kg (1000mg/kg) | BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) |
Personal Communication from LONZA Ltd., CH-4002, Basel, SwitzerlandVol. 03FEB1981, |
rat | LD50 | oral | 2500mg/kg (2500mg/kg) | BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) | Personal Communication from LONZA Ltd., CH-4002, Basel, SwitzerlandVol. 03FEB1981, |
Consensus Reports:
Reported in EPA TSCA Inventory.
SAFETY PROFILE:
Moderately toxic by ingestion. When heated to decomposition it emits toxic fumes of NOx.
Hazard Codes of 1-Phenyl-3-methyl-5-aminopyrazole (CAS NO.1131-18-6): Xi,Xn
Risk Statements: 36/37/38-20/21/22
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36:Wear suitable protective clothing.
Standards and Recommendations:
Analytical Methods:
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