CAS No.:88321-09-9
Name: Aloxistatin
Details Introduction
TOXICITY DATA with REFERENCE:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | 3270mg/kg (3270mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: DYSPNEA |
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 17, Pg. 736, 1986. |
mouse | LD50 | oral | > 10gm/kg (10000mg/kg) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 17, Pg. 736, 1986. | |
mouse | LD50 | subcutaneous | > 7gm/kg (7000mg/kg) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 17, Pg. 736, 1986. | |
rat | LD50 | intraperitoneal | 2050mg/kg (2050mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: DYSPNEA |
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 17, Pg. 736, 1986. |
rat | LD50 | oral | > 10gm/kg (10000mg/kg) | SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) SKIN AND APPENDAGES (SKIN): HAIR: OTHER |
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 17, Pg. 736, 1986. |
rat | LD50 | subcutaneous | > 5gm/kg (5000mg/kg) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 17, Pg. 736, 1986. |
Consensus Reports:
SAFETY PROFILE:
Moderately toxic by intraperitoneal route. An experimental teratogen. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.Safety information of EST (CAS NO.88321-09-9):
Hazard Codes Xi
Risk Statements
36/37/38 Irritating to eyes, respiratory system and skin
Safety Statements
26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36 Wear suitable protective clothing
WGK Germany 2
RTECS RR0404300
Standards and Recommendations:
Analytical Methods:
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