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Current position:Home > Products > Aloxistatin

CAS No.:88321-09-9

Name: Aloxistatin

Details Introduction

TOXICITY DATA with REFERENCE:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 3270mg/kg (3270mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: ATAXIA

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 17, Pg. 736, 1986.
mouse LD50 oral > 10gm/kg (10000mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 17, Pg. 736, 1986.
mouse LD50 subcutaneous > 7gm/kg (7000mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 17, Pg. 736, 1986.
rat LD50 intraperitoneal 2050mg/kg (2050mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: ATAXIA

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 17, Pg. 736, 1986.
rat LD50 oral > 10gm/kg (10000mg/kg) SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

SKIN AND APPENDAGES (SKIN): HAIR: OTHER
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 17, Pg. 736, 1986.
rat LD50 subcutaneous > 5gm/kg (5000mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 17, Pg. 736, 1986.


Consensus Reports:

 


SAFETY PROFILE:

Moderately toxic by intraperitoneal route. An experimental teratogen. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.Safety information of EST (CAS NO.88321-09-9):
Hazard Codes  IrritantXi
Risk Statements 
36/37/38 Irritating to eyes, respiratory system and skin
Safety Statements 
26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36 Wear suitable protective clothing
WGK Germany  2
RTECS  RR0404300


Standards and Recommendations:

 


Analytical Methods:

 


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