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Current position:Home > Products > Benperidol

CAS No.:2062-84-2

Name: Benperidol

Details Introduction

TOXICITY DATA with REFERENCE:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 250mg/kg (250mg/kg) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

BEHAVIORAL: REGIDITY
Farmaco, Edizione Scientifica. Vol. 35, Pg. 605, 1980.
mouse LD50 intravenous 20mg/kg (20mg/kg)   U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#11942,
mouse LD50 oral 432mg/kg (432mg/kg) BEHAVIORAL: ATAXIA

BEHAVIORAL: REGIDITY

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 61, Pg. 421, 1965.
mouse LD50 subcutaneous 204mg/kg (204mg/kg) BEHAVIORAL: ATAXIA

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

BEHAVIORAL: REGIDITY
Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 61, Pg. 421, 1965.
rat LD50 intravenous 21mg/kg (21mg/kg)   Psychopharmacology Service Center, Bulletin. Vol. 2, Pg. 17, 1963.
rat LD50 subcutaneous 220mg/kg (220mg/kg) SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE

AUTONOMIC NERVOUS SYSTEM: CENTRAL SYMPATHOLYTIC

BEHAVIORAL: ALTERATION OF CLASSICAL CONDITIONING
Medicinal Chemistry


Consensus Reports:

 


SAFETY PROFILE:

Poison by subcutaneous, intravenous, and intraperitoneal routes. When heated to decomposition it emits toxic fumes of F and NOx.


Standards and Recommendations:

 


Analytical Methods:

 


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