CAS No.:2062-84-2
Name: Benperidol
Details Introduction
TOXICITY DATA with REFERENCE:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | 250mg/kg (250mg/kg) | BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) BEHAVIORAL: REGIDITY |
Farmaco, Edizione Scientifica. Vol. 35, Pg. 605, 1980. |
mouse | LD50 | intravenous | 20mg/kg (20mg/kg) | U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#11942, | |
mouse | LD50 | oral | 432mg/kg (432mg/kg) | BEHAVIORAL: ATAXIA BEHAVIORAL: REGIDITY LUNGS, THORAX, OR RESPIRATION: DYSPNEA |
Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 61, Pg. 421, 1965. |
mouse | LD50 | subcutaneous | 204mg/kg (204mg/kg) | BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: REGIDITY |
Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 61, Pg. 421, 1965. |
rat | LD50 | intravenous | 21mg/kg (21mg/kg) | Psychopharmacology Service Center, Bulletin. Vol. 2, Pg. 17, 1963. | |
rat | LD50 | subcutaneous | 220mg/kg (220mg/kg) | SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE AUTONOMIC NERVOUS SYSTEM: CENTRAL SYMPATHOLYTIC BEHAVIORAL: ALTERATION OF CLASSICAL CONDITIONING |
Medicinal Chemistry |
Consensus Reports:
SAFETY PROFILE:
Poison by subcutaneous, intravenous, and intraperitoneal routes. When heated to decomposition it emits toxic fumes of F− and NOx.
Standards and Recommendations:
Analytical Methods:
Related Searches
Other Product
- -
- -
- -
- -
- -
- -
- -
- -
- -
- (4S,6R)-6-{2-[(2-hydroxy-ethyl)-(4-methoxy-benzenesulfonyl)-amino]-ethoxy}-4-isopropyl-5,6-dihydro-4H-pyran-2-carboxylic acid allyl ester
- [1,4'-Bipiperidine]-1'-carboxylic acid, 4-(1H-indol-7-yl)-, ethyl ester
- 1,3,5-Tris(4-acetamidophenyl)penta-1,5-dione
- 1,5-Bis(3-aminophenyl)-3-(4-N,N-di-methylaminophenyl)penta-1,5-dione
- 1,5-Bis(4-acetamidophenyl)-3-phenylpenta-1,5-dione
- 1,5-Bis(4-aminophenyl)-3-(4-acetamido-phenyl)penta-1,5-dione
- 1,5-Bis(4-aminophenyl)-3-phenylpenta-1,5-dione