CAS No.:41575-94-4

TOXICITY DATA with REFERENCE：

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	intravenous	> 31200ug/kg (31.2mg/kg)		Drugs in Japan Vol. -, Pg. 288, 1990.
mammal (species unspecified)	LD50	unreported	158mg/kg (158mg/kg)		Yaoxue Xuebao. Acta Pharmaceutica Sinica. Pharmaceutical Journal. Vol. 22, Pg. 56, 1987. Link to PubMed
mouse	LD50	intraperitoneal	118mg/kg (118mg/kg)		European Journal of Medicinal Chemistry--Chimie Therapeutique. Vol. 27, Pg. 611, 1992.
mouse	LD50	intravenous	89360ug/kg (89.36mg/kg)		National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program. Vol. JAN1986,
mouse	LD50	unreported	180mg/kg (180mg/kg)		Recent Results in Cancer Research. Vol. 48, Pg. 12, 1974.
rat	LD50	intravenous	60900ug/kg (60.9mg/kg)	SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	National Technical Information Service. Vol. PB288-374,
rat	LD50	oral	343mg/kg (343mg/kg)		Drugs in Japan Vol. -, Pg. 288, 1990.
rat	LD50	subcutaneous	72mg/kg (72mg/kg)		Drugs in Japan Vol. -, Pg. 288, 1990.

Consensus Reports：

 

SAFETY PROFILE：

Hazard Codes of Carboplatin (CAS NO.41575-94-4): T
Risk Statements: 46-61-20/21/22-42/43 
R46: May cause heritable genetic damage. 
R61: May cause harm to the unborn child. 
R20/21/22: Harmful by inhalation, in contact with skin and if swallowed. 
R42/43: May cause sensitization by inhalation and skin contact.
Safety Statements: 53-22-26-36/37/39-45 
S53: Avoid exposure - obtain special instructions before use. 
S22: Do not breathe dust. 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection. 
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR: 2811
WGK Germany: 3
 

Standards and Recommendations：

 

Analytical Methods：