CAS No.:77-65-6

TOXICITY DATA with REFERENCE：

1.		cyt-smc 10 mmol/tube		HEREAY    Hereditas. 33 (1947),457.
2.		ipr-rat LD50:427 mg/kg		ITMZBJ    Intensivmedizin. 17 (1980),305.
3.		ivn-rat LD50:427 mg/kg		ARTODN    Archives of Toxicology. 40 (1978),211.
4.		unr-rat LDLo:350 mg/kg		JPHAA3    Journal of the American Pharmaceutical Association. 23 (1934),788.
5.		orl-mus LD50:464 mg/kg		NCILB*    Progress Report for Contract No. NIH-NCI-E-C-72-3252, Submitted to the National Cancer Institute by Litton Bionetics, Inc. (Bethesda, MD) NIH-NCI-E-C-72-3252 (1973).
6.		orl-dog LD50:450 mg/kg		MEIEDD    Merck Index. 10 (1983),254.
7.		scu-dog LDLo:300 mg/kg		HBAMAK    “Abdernalden’s Handbuch der Biologischen Arbeitsmethoden.“ 4 (1935),1292.
8.		orl-cat LDLo:350 mg/kg		HBAMAK    “Abdernalden’s Handbuch der Biologischen Arbeitsmethoden.“ 4 (1935),1293.
9.		orl-rbt LDLo:600 mg/kg		SAPHAO    Skandinavisches Archiv fuer Physiologic. 28 (1913),193.
10.		scu-frg LDLo:1667 mg/kg		HBAMAK    “Abdernalden&rsqu

Consensus Reports：

NCI Carcinogenesis Bioassay (feed); No Evidence: mouse, rat NCITR*    National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD 20014) No. NCI-CG-TR-173 (1979). . Reported in EPA TSCA Inventory.

SAFETY PROFILE：

Poison by ingestion, subcutaneous, and possibly other routes. Moderately toxic via intravenous and intraperitoneal routes. Mutation data reported. A sedative, hypnotic, and central nervous system depressant. When heated to decomposition it emits very toxic fumes of NO_x and Br⁻.

Standards and Recommendations：

 

Analytical Methods：