CAS No.:2058-52-8
Name: Clothiapine
Details Introduction
TOXICITY DATA with REFERENCE：
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| guinea pig | LD50 | oral | 150mg/kg (150mg/kg) | Toxicology and Applied Pharmacology. Vol. 14, Pg. 657, 1969. | |
| mouse | LD50 | intramuscular | 160mg/kg (160mg/kg) | Drugs in Japan Vol. 6, Pg. 234, 1982. | |
| mouse | LD50 | intravenous | 46mg/kg (46mg/kg) | Drugs in Japan Vol. 6, Pg. 234, 1982. | |
| mouse | LD50 | oral | 270mg/kg (270mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 15, Pg. 841, 1965. | |
| mouse | LD50 | subcutaneous | 348mg/kg (348mg/kg) | Drugs in Japan Vol. 6, Pg. 234, 1982. | |
| rat | LD50 | intramuscular | > 300mg/kg (300mg/kg) | Drugs in Japan Vol. 6, Pg. 233, 1982. | |
| rat | LD50 | intravenous | 47mg/kg (47mg/kg) | Drugs in Japan Vol. -, Pg. 404, 1995. | |
| rat | LD50 | oral | 280mg/kg (280mg/kg) | Drugs in Japan Vol. 6, Pg. 234, 1982. | |
| rat | LD50 | subcutaneous | > 500mg/kg (500mg/kg) | Drugs in Japan Vol. 6, Pg. 233, 1982. |
Consensus Reports：
SAFETY PROFILE：
Poison by ingestion. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition Clothiapine (CAS NO.2058-52-8) emits very toxic fumes of Cl−, NOx, and SOx.
Standards and Recommendations：
Analytical Methods：
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