CAS No.:372-09-8
Name: Cyanoacetic acid
Details Introduction
TOXICITY DATA with REFERENCE:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
frog | LDLo | subcutaneous | 1300mg/kg (1300mg/kg) | LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 5, Pg. 161, 1899. |
mouse | LD50 | intraperitoneal | 200mg/kg (200mg/kg) | National Technical Information Service. Vol. AD691-490, | |
rabbit | LDLo | subcutaneous | 1900mg/kg (1900mg/kg) | PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION |
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 5, Pg. 161, 1899. |
rat | LD50 | oral | 1500mg/kg (1500mg/kg) | BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA SKIN AND APPENDAGES (SKIN): HAIR: OTHER |
Personal Communication from LONZA Ltd., CH-4002, Basel, SwitzerlandVol. 12JAN1981, |
Consensus Reports:
SAFETY PROFILE:
Hazard Codes: C
Risk Statements: 22-31-34-52/53-20/22
R22:Harmful if swallowed.
R31 :Contact with acids liberates toxic gas.
R34:Causes burns.
R52/53:Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
R20/22:Harmful by inhalation and if swallowed.
Safety Statements: 26-36/37/39-45-61-20
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S61:Avoid release to the environment. Refer to special instructions / safety data sheets.
S20:When using, do not eat or drink.
RIDADR: UN 3261 8/PG 2
WGK Germany: 2
RTECS: AG3675000
F: 3-10-21
HazardClass: 8
PackingGroup: II
Standards and Recommendations:
Analytical Methods:
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