CAS No.:72-55-9
Name: DDE
Details Introduction
TOXICITY DATA with REFERENCE:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
hamster | LD50 | oral | > 5gm/kg (5000mg/kg) | Laboratory Animal Science. Vol. 26, Pg. 274, 1976. | |
mouse | LD50 | oral | 700mg/kg (700mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 88, Pg. 400, 1946. | |
rat | LD50 | oral | 880mg/kg (880mg/kg) | Toxicology and Applied Pharmacology. Vol. 14, Pg. 515, 1969. |
Consensus Reports:
IARC Cancer Review: Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 5 (1974),p. 83.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . NCI Carcinogenesis Bioassay (feed); Clear Evidence: mouse NCITR* National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD 20014) No. NCI-CG-TR-131,78 . ; No Evidence: rat NCITR* National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD 20014) No. NCI-CG-TR-131,78 . . EPA Genetic Toxicology Program.
SAFETY PROFILE:
Safety Information of DDE (CAS NO.72-55-9):
Hazard Codes: Xn, N, T, F
Risk Statements: 22-40-50/53-52/53-39/23/24/25-23/24/25-11-67-65-38
R22: Harmful if swallowed
R40: Limited evidence of a carcinogenic effect
R50/53: Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment
R52/53: Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment
R23/24/25: Toxic by inhalation, in contact with skin and if swallowed
R11: Highly flammable
R67: Vapours may cause drowsiness and dizziness
R65: Harmful: may cause lung damage if swallowed
R38: Irritating to skin
Safety Statements: 36/37-60-61-45-16-7-62
S36/37: Wear suitable protective clothing and gloves
S60: This material and its container must be disposed of as hazardous waste
S61: Avoid release to the environment. Refer to special instructions / safety data sheets
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S16: Keep away from sources of ignition
S7: Keep container tightly closed
S62: If swallowed, do not induce vomitting; seek medical advice immediately and show this container or label
RIDADR: UN 3077 9/PG 3
WGK Germany: 3
RTECS: KV9450000
Suspected carcinogen with experimental carcinogenic and neoplastigenic data. Poison by ingestion. Experimental reproductive effects. Mutation data reported. An insecticide. When heated to decomposition it emits very toxic fumes of Cl−. See also CHLORINATED HYDROCARBONS, ALIPHATIC.
Standards and Recommendations:
Analytical Methods:
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