CAS No.:2391-03-9
Name: Dexbrompheniramine maleate
Details Introduction
TOXICITY DATA with REFERENCE:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
guinea pig | LD50 | oral | 259mg/kg (259mg/kg) | SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD |
Chemotherapia. Vol. 3, Pg. 120, 1961. |
mouse | LD50 | intraperitoneal | 106mg/kg (106mg/kg) | SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD |
Chemotherapia. Vol. 3, Pg. 120, 1961. |
mouse | LD50 | intravenous | 25mg/kg (25mg/kg) | SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: TREMOR |
Chemotherapia. Vol. 3, Pg. 120, 1961. |
mouse | LD50 | oral | 176mg/kg (176mg/kg) | SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD |
Chemotherapia. Vol. 3, Pg. 120, 1961. |
rat | LD50 | intraperitoneal | 104mg/kg (104mg/kg) | SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD |
Chemotherapia. Vol. 3, Pg. 120, 1961. |
rat | LD50 | oral | 191mg/kg (191mg/kg) | SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD |
Chemotherapia. Vol. 3, Pg. 120, 1961. |
Consensus Reports:
SAFETY PROFILE:
Hazard Codes of Dexbrompheniramine maleate (CAS NO.2391-03-9): T
Risk Statements: 25
R25 :Toxic if swallowed.
Safety Statements: 22-36/37/39-45
S22:Do not breathe dust.
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
Standards and Recommendations:
Analytical Methods:
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