CAS No.:77-67-8

TOXICITY DATA with REFERENCE：

1.		cyt-hmn:lyms 30 mg/L		MUREAV    Mutation Research. 204 (1988),623.
2.		orl-rat TDLo:66,600 µg/kg (6-14D preg):REP		40YJAX    Evaluation of Embryotoxicity, Mutagenicity and Carcinogenicity Risks In New Drugs Benesova, O., et al., eds.,Prague, Czechoslovakia.: Univerzita Karlova,1970,59.
3.		orl-mus LD50:1530 mg/kg		EPILAK    Epilepsia. 4 (4)(1963),66.
4.		ipr-mus LD50:1752 mg/kg		EPILAK    Epilepsia. 29 (1988),198.
5.		scu-mus LD50:1810 mg/kg		NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),117.
6.		ivn-mus LD50:780 mg/kg		NEPHBW    Neuropharmacology. 24 (1985),427.

Consensus Reports：

 

SAFETY PROFILE：

Safety Information of Ethosuximide (CAS NO.77-67-8):
Hazard Codes: Xn 
Risk Statements: 22
R22:Harmful if swallowed
Safety Statements: 36
S36:Wear suitable protective clothing
WGK Germany: 3
RTECS: WN2800000
Moderately toxic by ingestion, intravenous, subcutaneous, and intraperitoneal routes. Experimental teratogenic and reproductive effects. Mutation data reported. An anticonvulsant. When heated to decomposition it emits toxic fumes of NO_x.

Standards and Recommendations：

 

Analytical Methods：