CAS No.:30544-47-9
Name: Etofenamate
Details Introduction
TOXICITY DATA with REFERENCE:
1. |
orl-rat LD50:292 mg/kg |
ARZNAD Arzneimittel-Forschung. Drug Research. 27 (1977),1333. | ||
2. |
ipr-rat LD50:373 mg/kg |
ARZNAD Arzneimittel-Forschung. Drug Research. 27 (1977),1333. | ||
3. |
scu-rat LD50:568 mg/kg |
ARZNAD Arzneimittel-Forschung. Drug Research. 27 (1977),1333. | ||
4. |
ivn-rat LD50:139 mg/kg |
YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. 10 (1982),5225. | ||
5. |
orl-mus LD50:743 mg/kg |
ARZNAD Arzneimittel-Forschung. Drug Research. 27 (1977),1333. | ||
6. |
scu-mus LD50:1897 mg/kg |
YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. 10 (1982),5225. | ||
7. |
ivn-mus LD50:75 mg/kg |
YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. 10 (1982),5225. | ||
8. |
scu-rbt LD50:1532 mg/kg |
YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. 10 (1982),5225. |
Consensus Reports:
SAFETY PROFILE:
Poison by ingestion, intraperitoneal, and intravenous routes. Moderately toxic by subcutaneous routes. Experimental teratogenic and reproductive effects. Used as an anti-inflammatory agent. When heated to decomposition it emits very toxic fumes of F− and NOx. See also FLUORIDES.
Standards and Recommendations:
Analytical Methods:
Uv max (methanol): 286 (E1%1cm 423). nD25 1.564.
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