CAS No.:119006-77-8
Name: Flutrimazole
Details Introduction
TOXICITY DATA with REFERENCE:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | > 2gm/kg (2000mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: TREMOR LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION |
Arzneimittel-Forschung. Drug Research. Vol. 42, Pg. 841, 1992. |
mouse | LD50 | oral | > 1gm/kg (1000mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: TREMOR LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION |
Arzneimittel-Forschung. Drug Research. Vol. 42, Pg. 841, 1992. |
rat | LD50 | intraperitoneal | 1079mg/kg (1079mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: TREMOR LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION |
Arzneimittel-Forschung. Drug Research. Vol. 42, Pg. 841, 1992. |
rat | LD50 | oral | 808mg/kg (808mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: TREMOR LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION |
Arzneimittel-Forschung. Drug Research. Vol. 42, Pg. 841, 1992. |
Consensus Reports:
SAFETY PROFILE:
Flutrimazole (CAS NO.119006-77-8) may cause burning, irritation, pruritus and erythema in the treated zone. It shows a very low acute toxicity. Its topical administration does not cause sensitization and has no potential for inducing phototoxicity or photosensitivity.
Standards and Recommendations:
Analytical Methods:
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