CAS No.:544-13-8

TOXICITY DATA with REFERENCE：

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LDLo	subcutaneous	50mg/kg (50mg/kg)	GASTROINTESTINAL: NAUSEA OR VOMITING	Archives Internationales de Pharmacodynamie et de Therapie. Vol. 3, Pg. 77, 1897.
frog	LDLo	subcutaneous	3gm/kg (3000mg/kg)		Archives Internationales de Pharmacodynamie et de Therapie. Vol. 3, Pg. 77, 1897.
mouse	LD50	oral	266mg/kg (266mg/kg)		Pharmacochemistry Library. Vol. 8, Pg. 73, 1985.
pigeon	LDLo	subcutaneous	1200mg/kg (1200mg/kg)	GASTROINTESTINAL: NAUSEA OR VOMITING	Archives Internationales de Pharmacodynamie et de Therapie. Vol. 3, Pg. 77, 1897.
rabbit	LDLo	subcutaneous	18mg/kg (18mg/kg)	PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Archives Internationales de Pharmacodynamie et de Therapie. Vol. 3, Pg. 77, 1897.

Consensus Reports：

Cyanide and its compounds are on the Community Right-To-Know List. Reported in EPA TSCA Inventory.

SAFETY PROFILE：

Poison by subcutaneous route. Moderately toxic by ingestion. When heated to decomposition it emits very toxic fumes of NO_x and CN⁻. See also NITRILES.
Hazard Codes:
Xn: Harmful
Risk Statements about 1,3-Trimethylenedinitrile (544-13-8):
R20/21/22 Harmful by inhalation, in contact with skin and if swallowed. 
R36/38 Irritating to eyes and skin. 
Safety Statements about 1,3-Trimethylenedinitrile (544-13-8):
S22 Do not breathe dust. 
S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36/37/39 Wear suitable protective clothing, gloves and eye/face protection.
Attentions:
1. Storage: Store in a cool, dry place. Store in a tightly closed container.
2. Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Avoid ingestion and inhalation.

Standards and Recommendations：

 

Analytical Methods：