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Current position:Home > Products > Isonicotinic acid

CAS No.:55-22-1

Name: Isonicotinic acid

Details Introduction

TOXICITY DATA with REFERENCE:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 436mg/kg (436mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)
Pharmaceutical Chemistry Journal Vol. 11, Pg. 481, 1977.
mouse LD50 intravenous 5gm/kg (5000mg/kg)   Therapie. Vol. 23, Pg. 1343, 1968.
mouse LD50 oral 3123mg/kg (3123mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)
Pharmaceutical Chemistry Journal Vol. 11, Pg. 481, 1977.
rat LD50 oral 5gm/kg (5000mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)
Pharmaceutical Chemistry Journal Vol. 11, Pg. 481, 1977.


Consensus Reports:

Reported in EPA TSCA Inventory.


SAFETY PROFILE:

Moderately toxic by ingestion and intraperitoneal routes. Mildly toxic by intravenous route. When heated to decomposition it emits toxic fumes of NOx.
Hazard Codes: IrritantXi
Risk Statements information:
36/37/38:  Irritating to eyes, respiratory system and skin 
Safety Statements information:
26:  In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 
36:  Wear suitable protective clothing 
WGK Germany: 2


Standards and Recommendations:

 


Analytical Methods:

 


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