CAS No.:62-46-4

TOXICITY DATA with REFERENCE：

 

Consensus Reports：

 

SAFETY PROFILE：

 

Standards and Recommendations：

  Lipoic acid (CAS NO.62-46-4) is first called pyruvate oxidation factor  by Irwin C. Gunsalus, the former chair of Biochemistry at the University of Illinois at Urbana-Champaign. The structure was determined in a collaboration of Gunsalus with Lester Reed and Eli Lilly; the synthetic compound designated α-lipoic acid proved to be the correct molecule. The configuration found in vivo was later found to be the R-enantiomer.This was after the observation by many groups that POF functioned as an essential growth factor for Enterococci, which lack the ability to make lipoate.

Analytical Methods：