CAS No.:74-31-7

TOXICITY DATA with REFERENCE：

1.		eye-rbt 500 mg/24H SEV		28ZPAK    Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku Marhold, J.V.,Institut Pro Vychovu Vedoucicn Pracovniku Chemickeho Prumyclu Praha,Czechoslovakia.: 1972,73.
2.		mma-sat 10 µg/plate		PCBRD2    Progress in Clinical and Biological Research. 141 (1984),407.
3.		msc-ham:lng 30 mg/L		SWEHDO    Scandinavian Journal of Work, Environment and Health. 9 (Suppl 2)(1983),27.
4.		orl-rat LD50:2370 mg/kg		28ZPAK    Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku Marhold, J.V.,Institut Pro Vychovu Vedoucicn Pracovniku Chemickeho Prumyclu Praha,Czechoslovakia.: 1972,73.
5.		orl-mus LD50:18 g/kg		GTPZAB    Gigiena Truda i Professionalnye Zabolevaniia. Labor Hygiene and Occupational Diseases. 10 (3)(1966),49.
6.		ipr-mus LD50:300 mg/kg		NTIS**    National Technical Information Service. (Springfield, VA 22161) (Formerly U.S. Clearinghouse for Scientific and Technical Information) AD277-689 .

Consensus Reports：

Reported in EPA TSCA Inventory.

SAFETY PROFILE：

Poison by intraperitoneal route. Moderately toxic by ingestion. A weak allergen. Experimental teratogenic and reproductive effects. An eye irritant. Questionable carcinogen with experimental tumorigenic data. Mutation data reported. Combustible when exposed to heat or flame; can react with oxidizing materials. When heated to decomposition it emits toxic fumes of NO_x.
Hazard Codes:
Xi: Irritant 
Risk Statements about 1,4-bis(phenyl amino)Benzene (74-31-7):
R 43 May cause sensitization by skin contact. 
R 52/53 Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Safety Statements about 1,4-bis(phenyl amino)Benzene (74-31-7):
S 24 Avoid contact with skin. 
S 37 Wear suitable gloves. 
S 61 Avoid release to the environment. Refer to special instructions/safety data sheets.
Attentions:
1. Storage: Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
2. Handling: All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.

Standards and Recommendations：

 

Analytical Methods：