CAS No.:1456-28-6
Name: N-Nitroso-2,6-dimethylmorpholine
Details Introduction
TOXICITY DATA with REFERENCE:
1. |
mmo-sat 1 mg/plate |
TCMUD8 Teratogenesis, Carcinogenesis, and Mutagenesis. 1 (1980),295. | ||
2. |
mma-sat 50 nmol/plate |
MUREAV Mutation Research. 57 (1978),1. | ||
3. |
dns-rat:lvr 1 mmol/L |
MUREAV Mutation Research. 144 (1985),197. | ||
4. |
scu-rat LD50:387 mg/kg |
CALEDQ Cancer Letters (Shannon, Ireland). 13 (1981),159. | ||
5. |
orl-gpg LD50:280 mg/kg |
JJIND8 JNCI, Journal of the National Cancer Institute. 64 (1980),529. | ||
6. |
orl-ham LD50:367 mg/kg |
JNCIAM Journal of the National Cancer Institute. 58 (1977),429. | ||
7. |
scu-ham LD50:320 mg/kg |
JNCIAM Journal of the National Cancer Institute. 60 (1978),197. |
Consensus Reports:
EPA Genetic Toxicology Program.
SAFETY PROFILE:
Suspected carcinogen with experimental carcinogenic, tumorigenic, and neoplastigenic data. Poison by ingestion and subcutaneous routes. Mutation data reported. Used as a model carcinogenic and carcinogenic metabolite. When heated to decomposition N-Nitroso-2,6-dimethylmorpholine (CAS NO.1456-28-6) emits toxic fumes of NOx. See also N-NITROSO COMPOUNDS.
Standards and Recommendations:
Analytical Methods:
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