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Current position:Home > Products > N-Nitroso-2,6-dimethylmorpholine

CAS No.:1456-28-6

Name: N-Nitroso-2,6-dimethylmorpholine

Details Introduction

TOXICITY DATA with REFERENCE:

1.    

mmo-sat 1 mg/plate

    TCMUD8    Teratogenesis, Carcinogenesis, and Mutagenesis. 1 (1980),295.
2.    

mma-sat 50 nmol/plate

    MUREAV    Mutation Research. 57 (1978),1.
3.    

dns-rat:lvr 1 mmol/L

    MUREAV    Mutation Research. 144 (1985),197.
4.    

scu-rat LD50:387 mg/kg

    CALEDQ    Cancer Letters (Shannon, Ireland). 13 (1981),159.
5.    

orl-gpg LD50:280 mg/kg

    JJIND8    JNCI, Journal of the National Cancer Institute. 64 (1980),529.
6.    

orl-ham LD50:367 mg/kg

    JNCIAM    Journal of the National Cancer Institute. 58 (1977),429.
7.    

scu-ham LD50:320 mg/kg

    JNCIAM    Journal of the National Cancer Institute. 60 (1978),197.

Consensus Reports:

EPA Genetic Toxicology Program.


SAFETY PROFILE:

Suspected carcinogen with experimental carcinogenic, tumorigenic, and neoplastigenic data. Poison by ingestion and subcutaneous routes. Mutation data reported. Used as a model carcinogenic and carcinogenic metabolite. When heated to decomposition N-Nitroso-2,6-dimethylmorpholine (CAS NO.1456-28-6) emits toxic fumes of NOx. See also N-NITROSO COMPOUNDS.


Standards and Recommendations:

 


Analytical Methods:

 


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