CAS No.:556-88-7

TOXICITY DATA with REFERENCE：

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
guinea pig	LD50	oral	3120mg/kg (3120mg/kg)	LUNGS, THORAX, OR RESPIRATION: CYANOSIS	Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 45(1), Pg. 18, 1980.
mouse	LD50	intraperitoneal	48mg/kg (48mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Pharmaceutical Chemistry Journal Vol. 10, Pg. 1504, 1976.
mouse	LD50	oral	3850mg/kg (3850mg/kg)	LUNGS, THORAX, OR RESPIRATION: CYANOSIS	Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 45(1), Pg. 18, 1980.
rabbit	LD	skin	> 2gm/kg (2000mg/kg)		National Technical Information Service. Vol. AD-A191-796,
rat	LD50	oral	10200mg/kg (10200mg/kg)	LUNGS, THORAX, OR RESPIRATION: CYANOSIS	Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 45(1), Pg. 18, 1980.

Consensus Reports：

Reported in EPA TSCA Inventory.

SAFETY PROFILE：

Poison by intraperitoneal route. Moderately toxic by ingestion. Mutation data reported. A very dangerous fire hazard when exposed to heat, flame, or by chemical reaction with oxidizers. A severe explosion hazard when shocked or exposed to heat or flame. It is about as powerful as TNT. It is normally mixed with colloided nitrocellulose or ammonium nitrate and paraffin wax. Can react vigorously with oxidizing materials and the derivatives can be explosive. The mercury and silver salts and other derivatives are much more impact-sensitive. When heated to decomposition it emits highly toxic fumes of NO_x. See also NITRO COMPOUNDS.
Hazard Codes:
F: Flammable
Xi: Irritant
Risk Statements about Nitroguanidine (CAS NO.556-88-7):
R5 Heating may cause an explosion.
R11 Highly flammable. 
R36/37/38 Irritating to eyes, respiratory system and skin. 
Safety Statements about α-Nitroguanidine (CAS NO.556-88-7):
S16 Keep away from sources of ignition - No smoking. 
S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S37/39 Wear suitable gloves and eye/face protection. 
S47 Keep at temperature not exceeding ...°C (to be specified by the manufacturer).

Standards and Recommendations：

DOT Classification:  EXPLOSIVE 1.1D; Label: EXPLOSIVE 1.1D (UN 0282); DOT Class: 4.1; Label: Flammable Solid (UN 1336)

Analytical Methods：