CAS No.:6493-05-6

TOXICITY DATA with REFERENCE：

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	239mg/kg (239mg/kg)		Arzneimittel-Forschung. Drug Research. Vol. 21, Pg. 1446, 1971.
mouse	LD50	intravenous	108mg/kg (108mg/kg)		Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 8, Pg. 267, 1977.
mouse	LD50	oral	1225mg/kg (1225mg/kg)		Drugs in Japan Vol. 6, Pg. 779, 1982.
mouse	LD50	subcutaneous	480mg/kg (480mg/kg)		Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 8, Pg. 267, 1977.
rabbit	LD50	intravenous	100mg/kg (100mg/kg)		Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 8, Pg. 267, 1977.
rat	LD50	intraperitoneal	230mg/kg (230mg/kg)	BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 9, Pg. 13, 1981.
rat	LD50	intravenous	231mg/kg (231mg/kg)		Arzneimittel-Forschung. Drug Research. Vol. 21, Pg. 1446, 1971.
rat	LD50	oral	1170mg/kg (1170mg/kg)	BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 9, Pg. 13, 1981.
rat	LD50	subcutaneous	375mg/kg (375mg/kg)		Oyo Yakuri. Pharmacometrics. Vol. 15, Pg. 153, 1978.
women	TDLo	oral	80mg/kg (80mg/kg)	CARDIAC: PULSE RATE	British Medical Journal. Vol. 288, Pg. 26, 1984.

Consensus Reports：

 

SAFETY PROFILE：

Hazard Codes Xn
Risk Statements 22
R22:Harmful if swallowed.
Safety Statements 36 
S36:Wear suitable protective clothing.
WGK Germany 3
RTECS XH2475000

Standards and Recommendations：

 

Analytical Methods：