CAS No.:51-71-8

TOXICITY DATA with REFERENCE：

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
child	TDLo	oral	7500ug/kg (7.5mg/kg)	behavioral: ataxia behavioral: somnolence (general depressed activity)	American Journal of Diseases of Children. Vol. 130, Pg. 507, 1976.
mouse	LD50	intraperitoneal	135mg/kg (135mg/kg)		Farmakologiya i Toksikologiya Vol. 32, Pg. 526, 1969.
mouse	LD50	oral	130mg/kg (130mg/kg)		Biochemical Pharmacology. Vol. 17, Pg. 369, 1968.
mouse	LD50	subcutaneous	122mg/kg (122mg/kg)		Farmakologiya i Toksikologiya Vol. 37, Pg. 651, 1974.
women	LDLo	oral	30mg/kg (30mg/kg)	lungs, thorax, or respiration: acute pulmonary edema liver: fatty liver degeration	Journal of Analytical Toxicology. Vol. 19, Pg. 265, 1995.
women	TDLo	oral	39600ug/kg/44 (39.6mg/kg)	behavioral: "hallucinations, distorted perceptions" behavioral: toxic psychosis behavioral: muscle contraction or spasticity)	Journal of Clinical Psychiatry. Vol. 48, Pg. 340, 1987.

Consensus Reports：

 

SAFETY PROFILE：

Poison by ingestion, intraperitoneal, and subcutaneous routes. Human systemic effects by ingestion: ataxia, somnolence. An experimental teratogen. Experimental reproductive effects. Mutation data reported. Used as an antidepressant. When heated to decomposition it emits toxic fumes of NO_x.
Hazard Codes:
Xi

Standards and Recommendations：

 

Analytical Methods：