CAS No.:114-86-3
Name: Phenformin
Details Introduction
TOXICITY DATA with REFERENCE:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
guinea pig | LD50 | subcutaneous | 16mg/kg (16mg/kg) | Medicina Experimentalis. Vol. 8, Pg. 237, 1963. | |
guinea pig | LDLo | intravenous | 30mg/kg (30mg/kg) | "Hemoperfusion: Kidney and Liver Support and Detoxification, Proceedings of the International Symposium, Haifa, 1979," Sideman, S., and T.M.S. Chang, eds., Multiple parts, New York, Hemisphere Pub. Corp., 1980-Vol. 1, Pg. 337, 1980. | |
mouse | LD50 | intraperitoneal | 140mg/kg (140mg/kg) | Bollettino Chimico Farmaceutico. Vol. 97, Pg. 396, 1958. | |
mouse | LD50 | oral | 450mg/kg (450mg/kg) | Acta Poloniae Pharmaceutica. For English translation, see APPFAR. Vol. 42, Pg. 236, 1985. | |
rat | LD50 | oral | 650mg/kg (650mg/kg) | Acta Poloniae Pharmaceutica. For English translation, see APPFAR. Vol. 42, Pg. 236, 1985. |
Consensus Reports:
SAFETY PROFILE:
Poison by intraperitoneal, subcutaneous, and intravenous routes. Moderately toxic by ingestion. When heated to decomposition it emits toxic fumes of NOx.Safety information of Phenformin (CAS NO.114-86-3):
Hazard Codes: Xn
Risk Statements: 22
R22:Harmful if swallowed.
Safety Statements: 36
S36:Wear suitable protective clothing.
WGK Germany: 3
RTECS: DU2200000
Standards and Recommendations:
Analytical Methods:
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