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CAS No.:5016-18-2

Name: Reumycin

Details Introduction

TOXICITY DATA with REFERENCE:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 44700ug/kg (44.7mg/kg) KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)"

BLOOD: CHANGES IN SPLEEN
Antibiotiki. Vol. 21, Pg. 178, 1976.
mouse LD50 intravenous 45500ug/kg (45.5mg/kg) KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)"

BLOOD: CHANGES IN SPLEEN
Antibiotiki. Vol. 21, Pg. 178, 1976.
mouse LD50 oral 128mg/kg (128mg/kg) KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)"

BLOOD: CHANGES IN SPLEEN
Antibiotiki. Vol. 21, Pg. 178, 1976.
rabbit LD50 intravenous > 34mg/kg (34mg/kg)   Antibiotiki. Vol. 21, Pg. 178, 1976.
rat LD50 intraperitoneal 41600ug/kg (41.6mg/kg)   Antibiotiki. Vol. 21, Pg. 178, 1976.
rat LD50 intravenous 42200ug/kg (42.2mg/kg)   Antibiotiki. Vol. 21, Pg. 178, 1976.

Consensus Reports:

 


SAFETY PROFILE:

A poison by ingestion, intraperitoneal, and intravenous routes. When heated to decomposition it emits toxic vapors of NOx.


Standards and Recommendations:

 


Analytical Methods:

 


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