CAS No.:5016-18-2
Name: Reumycin
Details Introduction
TOXICITY DATA with REFERENCE:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | 44700ug/kg (44.7mg/kg) | KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)" BLOOD: CHANGES IN SPLEEN |
Antibiotiki. Vol. 21, Pg. 178, 1976. |
mouse | LD50 | intravenous | 45500ug/kg (45.5mg/kg) | KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)" BLOOD: CHANGES IN SPLEEN |
Antibiotiki. Vol. 21, Pg. 178, 1976. |
mouse | LD50 | oral | 128mg/kg (128mg/kg) | KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)" BLOOD: CHANGES IN SPLEEN |
Antibiotiki. Vol. 21, Pg. 178, 1976. |
rabbit | LD50 | intravenous | > 34mg/kg (34mg/kg) | Antibiotiki. Vol. 21, Pg. 178, 1976. | |
rat | LD50 | intraperitoneal | 41600ug/kg (41.6mg/kg) | Antibiotiki. Vol. 21, Pg. 178, 1976. | |
rat | LD50 | intravenous | 42200ug/kg (42.2mg/kg) | Antibiotiki. Vol. 21, Pg. 178, 1976. |
Consensus Reports:
SAFETY PROFILE:
A poison by ingestion, intraperitoneal, and intravenous routes. When heated to decomposition it emits toxic vapors of NOx.
Standards and Recommendations:
Analytical Methods:
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