CAS No.:81-88-9

TOXICITY DATA with REFERENCE：

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	144mg/kg (144mg/kg)		"Recent Advances of Chemistry and Molecular Biology in Cancer Research, Insternational Symposium on Recent Advances of Chemistry and Molecular Biology in Cancer Research, Held in Beijing/China, July 23rd-26th, 1991" Dai Qianhuan, Margaret-Ann Armour and Zheng Qingying eds. Science Press Vol. -, Pg. 281, 1993.
mouse	LD50	oral	887mg/kg (887mg/kg)		Toxicological European Research. Vol. 1, Pg. 23, 1978.
mouse	LD50	subcutaneous	180mg/kg (180mg/kg)		Osaka-furitsu Koshu Eisei Kenkyusho Kenkyu Hokoku, Koshu Eisei Hen. Research Reports of the Oaka Prefectural Institute of Public Health, Public Health Section. Vol. (3), Pg. 185, 1953.
rat	LD50	intraperitoneal	112mg/kg (112mg/kg)		Toxicological European Research. Vol. 1, Pg. 23, 1978.
rat	LD50	intravenous	89mg/kg (89mg/kg)		Toxicology and Applied Pharmacology. Vol. 3, Pg. 696, 1961.
rat	LDLo	oral	500mg/kg (500mg/kg)		National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. Vol. 5, Pg. 8, 1953.

Consensus Reports：

 

SAFETY PROFILE：

Hazard Codes of Rhodamine B (CAS NO.81-88-9): Xn,Xi,F
Risk Statements: 22-41-68-67-36-11
R22: Harmful if swallowed. 
R41: Risk of serious damage to the eyes. 
R68: Possible risk of irreversible effects. 
R67: Vapours may cause drowsiness and dizziness. 
R36: Irritating to eyes. 
R11: Highly flammable.
Safety Statements: 7-16-24/25-26-36/37/39 
S7: Keep container tightly closed. 
S16: Keep away from sources of ignition. 
S24/25: Avoid contact with skin and eyes. 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.
WGK Germany: 2
 

Standards and Recommendations：

 

Analytical Methods：