CAS No.:9001-99-4
Name: Ribonuclease A
Details Introduction
TOXICITY DATA with REFERENCE:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intramuscular | 355mg/kg (355mg/kg) | "Nukleazy: Biologicheskaya Rol i Prakticheskoe Ispol'zovanie. Nucleases: Biological Function and Practical Applications," Berdyshev, G.D., et al., eds., Kiev, USSR, Izdatel'stvo Naukova Dumka, 1985Vol. -, Pg. 56, 1985. | |
mouse | LD50 | intraperitoneal | 250mg/kg (250mg/kg) | "Nukleazy: Biologicheskaya Rol i Prakticheskoe Ispol'zovanie. Nucleases: Biological Function and Practical Applications," Berdyshev, G.D., et al., eds., Kiev, USSR, Izdatel'stvo Naukova Dumka, 1985Vol. -, Pg. 56, 1985. | |
mouse | LD50 | subcutaneous | 230mg/kg (230mg/kg) | "Nukleazy: Biologicheskaya Rol i Prakticheskoe Ispol'zovanie. Nucleases: Biological Function and Practical Applications," Berdyshev, G.D., et al., eds., Kiev, USSR, Izdatel'stvo Naukova Dumka, 1985Vol. -, Pg. 56, 1985. | |
rat | LD50 | intramuscular | 310mg/kg (310mg/kg) | "Nukleazy: Biologicheskaya Rol i Prakticheskoe Ispol'zovanie. Nucleases: Biological Function and Practical Applications," Berdyshev, G.D., et al., eds., Kiev, USSR, Izdatel'stvo Naukova Dumka, 1985Vol. -, Pg. 56, 1985. | |
rat | LD50 | intraperitoneal | 392mg/kg (392mg/kg) | "Nukleazy: Biologicheskaya Rol i Prakticheskoe Ispol'zovanie. Nucleases: Biological Function and Practical Applications," Berdyshev, G.D., et al., eds., Kiev, USSR, Izdatel'stvo Naukova Dumka, 1985Vol. -, Pg. 56, 1985. | |
rat | LD50 | subcutaneous | 290mg/kg (290mg/kg) | "Nukleazy: Biologicheskaya Rol i Prakticheskoe Ispol'zovanie. Nucleases: Biological Function and Practical Applications," Berdyshev, G.D., et al., eds., Kiev, USSR, Izdatel'stvo Naukova Dumka, 1985Vol. -, Pg. 56, 1985. |
Consensus Reports:
SAFETY PROFILE:
Safety Statements:
S22:Do not breathe dust.
S24/25:Avoid contact with skin and eyes.
WGK Germany: 3
RTECS: RF0760000
F 10: Keep under argon.
F 21: Sensitive to humidity.
Standards and Recommendations:
Analytical Methods:
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