CAS No.:341031-54-7
Name: Sunitinib malate
Details Introduction
TOXICITY DATA with REFERENCE:
Consensus Reports:
SAFETY PROFILE:
Standards and Recommendations:
Analytical Methods:
Sunitinib inhibits cellular signaling by targeting multiple receptor tyrosine kinases.These include all receptors for platelet-derived growth factor and vascular endothelial growth factor receptors ,which play a role in both tumor angiogenesis and tumor cell proliferation. The simultaneous inhibition of these targets therefore leads to both reduced tumor vascularization and cancer cell death, and ultimately tumor shrinkage.
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