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CAS No.:341031-54-7

Name: Sunitinib malate

Details Introduction

TOXICITY DATA with REFERENCE:

 


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Analytical Methods:

Sunitinib inhibits cellular signaling by targeting multiple receptor tyrosine kinases.These include all receptors for platelet-derived growth factor  and vascular endothelial growth factor receptors ,which play a role in both tumor angiogenesis and tumor cell proliferation. The simultaneous inhibition of these targets therefore leads to both reduced tumor vascularization and cancer cell death, and ultimately tumor shrinkage.


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