CAS No.:50-52-2
Name: Thioridazine
Details Introduction
TOXICITY DATA with REFERENCE:
1. |
sln-dmg-orl 100 mg/L |
IJEBA6 Indian Journal of Experimental Biology. 11 (1973),403. | ||
2. |
orl-cld TDLo:28 mg/kg/2W-I |
AJPSAO American Journal of Psychiatry. 143 (1985),1176. | ||
3. |
orl-cld TDLo:28 mg/kg/2W-I:BAH |
AJPSAO American Journal of Psychiatry. 143 (1985),1176. | ||
4. |
orl-wmn TDLo:14,500 mg/kg/15Y-I:EYE |
CMAJAX Canadian Medical Association Journal. 132 (1985),737. | ||
5. |
orl-hmn LDLo:43 mg/kg |
ARGPAQ Archives of General Psychiatry. 34 (1977),955. | ||
6. |
orl-chd TDLo:25 mg/kg:CNS,CVS |
AJDCAI American Journal of Diseases of Children. 130 (1976),507. | ||
7. |
orl-hmn TDLo:24 mg/kg:ANS AACRAT 52,938,73 |
|||
8. |
orl-rat LD50:995 mg/kg |
TXAPA9 Toxicology and Applied Pharmacology. 18 (1971),185. | ||
9. |
ipr-rat LD50:150 mg/kg |
PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. 10 (1976),1001. | ||
10. |
scu-rat LD50:640 mg/kg |
MDCHAG Medicinal Chemistry: A Series of Monographs. 4 (1967),199. | ||
|
Consensus Reports:
EPA Genetic Toxicology Program.
SAFETY PROFILE:
Human poison by ingestion. Experimental poison by ingestion, subcutaneous, and intraperitoneal routes. Human systemic effects by ingestion: heart rate change, muscle contraction or spasticity, parasympatholytic, toxic psychosis, visual field and retinal changes. Human reproductive effects. Experimental reproductive effects. Mutation data reported. An antipsychotic and sedative. When heated to decomposition it emits very toxic fumes of NOx and SOx.
Standards and Recommendations:
Analytical Methods:
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