CAS No.:137-26-8

TOXICITY DATA with REFERENCE：

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
bird - wild	LD50	oral	300mg/kg (300mg/kg)		Archives of Environmental Contamination and Toxicology. Vol. 12, Pg. 355, 1983.
cat	LDLo	oral	230mg/kg (230mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ATAXIA BEHAVIORAL: ANALGESIA	Journal of Pharmacology and Experimental Therapeutics. Vol. 17, Pg. 349, 1921.
chicken	LD50	unreported	840mg/kg (840mg/kg)		Veterinariya. Veterinary Science. Vol. 54(2), Pg. 70, 1978.
domestic animals - goat/sheep	LD50	unreported	225mg/kg (225mg/kg)		Veterinariya. Veterinary Science. Vol. 54(2), Pg. 70, 1978.
human	TCLo	inhalation	30ug/m3/5Y-I (0.03mg/m3)	SENSE ORGANS AND SPECIAL SENSES: CONJUNCTIVE IRRITATION: EYE CARDIAC: OTHER CHANGES LUNGS, THORAX, OR RESPIRATION: STRUCTURAL OR FUNCTIONAL CHANGE IN TRACHEA OR BRONCHI	Vrachebnoe Delo. Medical Practice. Vol. (10), Pg. 136, 1971.
mammal (species unspecified)	LD50	unreported	400mg/kg (400mg/kg)		Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 45(5), Pg. 29, 1980.
mouse	LD50	intraperitoneal	70mg/kg (70mg/kg)		Drugs in Japan Vol. 6, Pg. 566, 1982.
mouse	LD50	oral	1250mg/kg (1250mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) SKIN AND APPENDAGES (SKIN): HAIR: OTHER	Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 6(7), Pg. 28, 1962.
mouse	LD50	subcutaneous	1109mg/kg (1109mg/kg)		Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. Vol. 15, Pg. 507, 1990.
mouse	LD50	unreported	1150mg/kg (1150mg/kg)		Kobunshi Kako. Polymer Applications. Vol. 26, Pg. 358, 1977.
rabbit	LD50	oral	210mg/kg (210mg/kg)		Kobunshi Kako. Polymer Applications. Vol. 26, Pg. 358, 1977.
rabbit	LD50	unreported	210mg/kg (210mg/kg)		Veterinariya. Veterinary Science. Vol. 54(2), Pg. 70, 1978.
rabbit	LDLo	skin	1gm/kg (1000mg/kg)		"Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 110, 1982.
rat	LC50	inhalation	500mg/m3/4H (500mg/m3)		"Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986Vol. -, Pg. 1027, 1986.
rat	LD50	intraperitoneal	138mg/kg (138mg/kg)	BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)	Journal de Pharmacologie. Vol. 9, Pg. 35, 1978.
rat	LD50	oral	560mg/kg (560mg/kg)		Toxicology and Applied Pharmacology. Vol. 11, Pg. 546, 1967.
rat	LD50	subcutaneous	646mg/kg (646mg/kg)		Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. Vol. 15, Pg. 507, 1990.
rat	LD50	unreported	740mg/kg (740mg/kg)		Kobunshi Kako. Polymer Applications. Vol. 26, Pg. 358, 1977.
rat	LDLo	skin	5gm/kg (5000mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)	Acute Toxicity Data. Journal of the American College of Toxicology, Part B. Vol. 15(Suppl,

Consensus Reports：

 

SAFETY PROFILE：

Safety Information of Tetramethylthiuram disulfide (CAS NO. 137-26-8):
Hazard Codes: Xn ,N 
Risk Statements: 20/22-36/38-43-48/22-50/53
R20/22:Harmful by inhalation and if swallowed
R36/38:Irritating to eyes and skin
R43:May cause sensitization by skin contact
R48/22:Harmful: danger of serious damage to health by prolonged exposure if swallowed
R50/53:Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment
Safety Statements: 26-36/37-60-61
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36/37:Wear suitable protective clothing and gloves
S60:This material and its container must be disposed of as hazardous waste
S61:Avoid release to the environment. Refer to special instructions / safety data sheets
RIDADR: UN 2771/2811
WGK Germany: 3
RTECS: JO1400000
HazardClass: 9
PackingGroup: III
HS Code: 29303000

Standards and Recommendations：

 

Analytical Methods：