CAS No.:280-57-9

TOXICITY DATA with REFERENCE：

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
guinea pig	LD50	oral	2250mg/kg (2250mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)	Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 45(5), Pg. 67, 1980.
rabbit	LD50	oral	1100mg/kg (1100mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)	Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 45(5), Pg. 67, 1980.
rat	LD50	oral	1700mg/kg (1700mg/kg)		Zeitschrift fuer die Gesamte Hygiene und Ihre Grenzgebiete. Vol. 20, Pg. 393, 1974.

Consensus Reports：

 

SAFETY PROFILE：

Moderately toxic by ingestion. A skin and eye irritant, allergen, and skin sensitizer. A powerful base. Forms an explosive complex with hydrogen peroxide. Mixtures with carbon auto-ignite at 230°C. Very exothermic reaction with cellulose nitrate. When heated to decomposition it emits toxic fumes of NO_x. See also AMINES. 
Hazard Codes: Xn,F
Risk Statements: 22-36/37/38-52/53-41-36/38-11 
R22:Harmful if swallowed. 
R36/37/38:Irritating to eyes, respiratory system and skin. 
R52/53:Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment. 
R41:Risk of serious damage to the eyes. 
R36/38:Irritating to eyes and skin. 
R11:Highly flammable.
Safety Statements: 26-60-37/39-3-16-36/37 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S60:This material and its container must be disposed of as hazardous waste. 
S37/39:Wear suitable gloves and eye/face protection. 
S3:Keep in a cool place. 
S16:Keep away from sources of ignition. 
S36/37:Wear suitable protective clothing and gloves.
RIDADR: UN 1325 4.1/PG 2
WGK Germany: 1
RTECS: HM0354200
F: 3
HazardClass: 8
PackingGroup: III
HS Code: 29335920

Standards and Recommendations：

 

Analytical Methods：