CAS No.:70-00-8
Name: Trifluridine
Details Introduction
TOXICITY DATA with REFERENCE:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
monkey | LDLo | intravenous | 400mg/kg (400mg/kg) | Government Reports Announcements. Vol. 74(9), Pg. 60, 1974. | |
mouse | LD50 | intraperitoneal | 1931mg/kg (1931mg/kg) | National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program. Vol. JAN1986, | |
mouse | LD50 | intravenous | 3381mg/kg (3381mg/kg) | Progress Report Submitted to the National Cancer Institute by Arthur D. Little, Inc. Vol. -, Pg. 260, 1967. | |
rat | LD50 | intravenous | 2946mg/kg (2946mg/kg) | LIVER: OTHER CHANGES | Progress Report Submitted to the National Cancer Institute by Arthur D. Little, Inc. Vol. -, Pg. 260, 1967. |
Consensus Reports:
SAFETY PROFILE:
Hazard Codes: Xn,
Xi
Risk Statements: 20/21/22-40
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
R40:Limited evidence of a carcinogenic effect.
Safety Statements: 22-36
S22:Do not breathe dust.
S36:Wear suitable protective clothing.
WGK Germany: 3
RTECS: XP2087500
Hazard Note: Keep Cold
Standards and Recommendations:
Analytical Methods:
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