CAS No.:3902-71-4
Name: Trioxsalen
Details Introduction
TOXICITY DATA with REFERENCE:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | > 3gm/kg (3000mg/kg) | Drugs in Japan Vol. -, Pg. 740, 1990. | |
mouse | LD50 | oral | > 7gm/kg (7000mg/kg) | Drugs in Japan Vol. 6, Pg. 520, 1982. | |
mouse | LD50 | subcutaneous | > 4gm/kg (4000mg/kg) | Drugs in Japan Vol. -, Pg. 740, 1990. | |
rat | LD50 | oral | > 22gm/kg (22000mg/kg) | Drugs in Japan Vol. 6, Pg. 520, 1982. |
Consensus Reports:
IARC Cancer Review: Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 , 1987,p. 366.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Human Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 40 , 1986,p. 357.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 40 , 1986,p. 357.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . Reported in EPA TSCA Inventory.
SAFETY PROFILE:
Moderately toxic by intraperitoneal and subcutaneous routes. Low toxicity by ingestion. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating vapors.
Hazard CodesC
Risk Statements 34-40
R34:Causes burns.
R40:Limited evidence of a carcinogenic effect.
Safety Statements 26-36/37/39-45
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR UN 1759 8/PG 1
WGK Germany 2
RTECS LV1576000
F 8-10
Standards and Recommendations:
Analytical Methods:
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