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Current position:Home > Products > Trioxsalen

CAS No.:3902-71-4

Name: Trioxsalen

Details Introduction

TOXICITY DATA with REFERENCE:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal > 3gm/kg (3000mg/kg)   Drugs in Japan Vol. -, Pg. 740, 1990.
mouse LD50 oral > 7gm/kg (7000mg/kg)   Drugs in Japan Vol. 6, Pg. 520, 1982.
mouse LD50 subcutaneous > 4gm/kg (4000mg/kg)   Drugs in Japan Vol. -, Pg. 740, 1990.
rat LD50 oral > 22gm/kg (22000mg/kg)   Drugs in Japan Vol. 6, Pg. 520, 1982.

 


Consensus Reports:

IARC Cancer Review: Group 3 IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 , 1987,p. 366.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Human Inadequate Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 40 , 1986,p. 357.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Inadequate Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 40 , 1986,p. 357.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . Reported in EPA TSCA Inventory.


SAFETY PROFILE:

Moderately toxic by intraperitoneal and subcutaneous routes. Low toxicity by ingestion. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating vapors.
Hazard CodesCorrosiveC
Risk Statements 34-40
R34:Causes burns. 
R40:Limited evidence of a carcinogenic effect.
Safety Statements 26-36/37/39-45
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection. 
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR UN 1759 8/PG 1
WGK Germany 2
RTECS LV1576000
F 8-10


Standards and Recommendations:

 


Analytical Methods:

 


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