CAS No.:13463-41-7

TOXICITY DATA with REFERENCE：

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	oral	600mg/kg (600mg/kg)		Clinical Toxicology. Vol. 13, Pg. 1, 1978. Link to PubMed
dog	LDLo	intravenous	25mg/kg (25mg/kg)	BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)	Toxicology and Applied Pharmacology. Vol. 9, Pg. 269, 1966. Link to PubMed
guinea pig	LD50	oral	> 2gm/kg (2000mg/kg)		Toxicology and Applied Pharmacology. Vol. 7, Pg. 425, 1965.
mammal (species unspecified)	LC50	inhalation	140mg/m3/4H (140mg/m3)		United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. Vol. 8EHQ-0790-1035,
monkey	LDLo	intravenous	25mg/kg (25mg/kg)	SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE	Toxicology and Applied Pharmacology. Vol. 9, Pg. 269, 1966.
mouse	LD50	intraperitoneal	26800ug/kg (26.8mg/kg)		Oyo Yakuri. Pharmacometrics. Vol. 8, Pg. 1067, 1974.
mouse	LD50	oral	160mg/kg (160mg/kg)		Clinical Toxicology. Vol. 13, Pg. 1, 1978.
mouse	LD50	subcutaneous	730mg/kg (730mg/kg)		Clinical Toxicology. Vol. 13, Pg. 1, 1978.
rabbit	LD50	skin	100mg/kg (100mg/kg)		Yakkyoku. Pharmacy. Vol. 32, Pg. 965, 1981.
rabbit	LDLo	intravenous	10mg/kg (10mg/kg)	BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)	Toxicology and Applied Pharmacology. Vol. 9, Pg. 269, 1966.
rat	LC50	inhalation	140mg/m3/4H (140mg/m3)	LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA LUNGS, THORAX, OR RESPIRATION: DYSPNEA	National Technical Information Service. Vol. OTS0527753-1,
rat	LD50	oral	177mg/kg (177mg/kg)		Toxicology Annual. Vol. 3, Pg. 1, 1979.

Consensus Reports：

 

SAFETY PROFILE：

Hazard Codes: T+
Risk Statements: 24/25-26-37/38-41 
R24/25: Toxic in contact with skin and if swallowed 
R26: Very Toxic by inhalation 
R37/38: Irritating to respiratory system and skin
R41: Risk of serious damage to the eyes
Safety Statements: 26-28-36/37/39-45 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S28: After contact with skin, wash immediately with plenty of soap-suds
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR: UN 2811 6.1/PG 2
WGK Germany: 3
RTECS: ZH0950000
HazardClass: 6.1(b)
PackingGroup: III

Standards and Recommendations：

 

Analytical Methods：