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CAS No.:500-34-5

Name: beta-Eucaine

Details Introduction

TOXICITY DATA with REFERENCE:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LDLo intravenous 10mg/kg (10mg/kg)   Physiological Reviews. Vol. 12, Pg. 190, 1932.
guinea pig LDLo intraperitoneal 18mg/kg (18mg/kg)   Physiological Reviews. Vol. 12, Pg. 190, 1932.
guinea pig LDLo intravenous 30mg/kg (30mg/kg)   Physiological Reviews. Vol. 12, Pg. 190, 1932.
guinea pig LDLo subcutaneous 310mg/kg (310mg/kg)   Physiological Reviews. Vol. 12, Pg. 190, 1932.
mouse LDLo intravenous 71mg/kg (71mg/kg) BEHAVIORAL: GENERAL ANESTHETIC "Vergleichend-pharmakologische Untersuchungen ueber die haemolytische Wirkung und die Toxizitat der Lokalanaesthetika, Dissertation," Walther, M., Pharmakologischen Instit Martin Luther-Universitat Halle-Wittenburg, Ger. Dem. Rep., 1936Vol. -, Pg. -, 1936.
rabbit LDLo subcutaneous 400mg/kg (400mg/kg)   Physiological Reviews. Vol. 12, Pg. 190, 1932.
rat LDLo intravenous 15mg/kg (15mg/kg)   Physiological Reviews. Vol. 12, Pg. 190, 1932.

Consensus Reports:

 


SAFETY PROFILE:

Poison by intravenous, subcutaneous, and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NOx.


Standards and Recommendations:

 


Analytical Methods:

 


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