CAS No.:110-57-6
Name: trans-1,4-Dichloro-2-butene
Details Introduction
TOXICITY DATA with REFERENCE:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
rat | LC50 | inhalation | 86ppm/4H (86ppm) | SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS |
Annual Meeting of American Industrial Hygiene Association. Vol. -, Pg. -, 1968. |
Consensus Reports:
IARC Cancer Review: Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 (1987),p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 15 (1977),p. 149.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . Reported in EPA TSCA Inventory. EPA Extremely Hazardous Substances List.
SAFETY PROFILE:
A poison by inhalation. Questionable carcinogen with experimental neoplastigenic and tumorigenic data. When heated to decomposition it emits toxic fumes of Cl−.
Hazard Codes: T+,T, F, N
HazardClass: 6.1(a)
Risk Statements:
10: Flammable
11: Highly Flammable
21: Harmful in contact with skin
25: Toxic if swallowed
26: Very Toxic by inhalation
34: Causes burns
45: May cause cancer
39/23/24/25: Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed
23/24/25: Toxic by inhalation, in contact with skin and if swallowed
24/25: Toxic in contact with skin and if swallowed
Safety Statements:
23: Do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer)
26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
60: This material and/or its container must be disposed of as hazardous waste
61: Avoid release to the environment. Refer to special instructions safety data sheet
36/37: Wear suitable protective clothing and gloves
36/37/39: Wear suitable protective clothing, gloves and eye/face protection
RIDADR: UN 3390 6.1/PG 1
WGK Germany: 3
RTECS: EM4903000
F: 8-21
PackingGroup: II
Standards and Recommendations:
Analytical Methods:
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