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Current position:Home > Products > trans-1,4-Dichloro-2-butene

CAS No.:110-57-6

Name: trans-1,4-Dichloro-2-butene

Details Introduction

TOXICITY DATA with REFERENCE:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
rat LC50 inhalation 86ppm/4H (86ppm) SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS
Annual Meeting of American Industrial Hygiene Association. Vol. -, Pg. -, 1968.


Consensus Reports:

IARC Cancer Review: Group 3 IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 (1987),p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Inadequate Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 15 (1977),p. 149.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . Reported in EPA TSCA Inventory. EPA Extremely Hazardous Substances List.


SAFETY PROFILE:

A poison by inhalation. Questionable carcinogen with experimental neoplastigenic and tumorigenic data. When heated to decomposition it emits toxic fumes of Cl.
Hazard Codes:   T+,ToxicT,   F,   N
HazardClass: 6.1(a)
Risk Statements:
10:  Flammable 
11:  Highly Flammable 
21:  Harmful in contact with skin 
25:  Toxic if swallowed 
26:  Very Toxic by inhalation 
34:  Causes burns 
45:  May cause cancer 
39/23/24/25:  Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed 
23/24/25:  Toxic by inhalation, in contact with skin and if swallowed 
24/25:  Toxic in contact with skin and if swallowed 
Safety Statements:
23:  Do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer) 
26:  In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 
60:  This material and/or its container must be disposed of as hazardous waste 
61:  Avoid release to the environment. Refer to special instructions safety data sheet 
36/37:  Wear suitable protective clothing and gloves 
36/37/39:  Wear suitable protective clothing, gloves and eye/face protection 
RIDADR: UN 3390 6.1/PG 1
WGK Germany: 3
RTECS: EM4903000
F: 8-21
PackingGroup: II


Standards and Recommendations:

 


Analytical Methods:

 


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